Evidence map›Paper›PMID 41367914›Full record

Observational studyFrontiers in endocrinology2025

Plasma corin levels provide minimal prognostic utility in left atrial reverse remodeling after catheter ablation of atrial fibrillation: an observational study.

Qianqian Wang, Yang Li, Xiaoyang Yuan, Yue Gong, Keyi Song, Chunkai Li, Jinqiu Liu, Yichang Zhao, Feifei Chen

Abstract readObservational Study
PubMed Full text at PMC Publisher
In one paragraph

Observational study in Frontiers in endocrinology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Qianqian Wang *Department of Cardiology, The First Affiliated Hospital of Dalian Medical University, Dalian, China.
Yang Li *Department of Cardiology, The First Affiliated Hospital of Dalian Medical University, Dalian, China.
Xiaoyang Yuan *Department of Laboratory Medicine, The First Affiliated Hospital of Dalian Medical University, Dalian, China.
Yue GongDepartment of Cardiology, Central Hospital of Dalian University of Technology, Dalian, China.
Keyi SongDepartment of Cardiology, The First Affiliated Hospital of Dalian Medical University, Dalian, China.
Chunkai LiDepartment of Cardiology, The First Affiliated Hospital of Dalian Medical University, Dalian, China.
Jinqiu LiuDepartment of Cardiology, The First Affiliated Hospital of Dalian Medical University, Dalian, China.
Yichang ZhaoDepartment of Cardiology, The First Affiliated Hospital of Dalian Medical University, Dalian, China.
Feifei ChenDepartment of Cardiology, The First Affiliated Hospital of Dalian Medical University, Dalian, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Objective: This study aims to assess the impact of plasma corin levels on left atrial reverse remodeling (LARR) in patients with atrial fibrillation (AF) after catheter ablation (CA). Methods: This prospective, single-center, observational study included 335 patients undergoing first CA of AF. All patients underwent at least two echocardiographic examinations at intervals of ≥3 months. Corin was measured before and 1 day after CA. LARR was defined as a reduction of ≥20% in left atrial volume index. Results: After a median of 29.53 months of follow-up, 94 patients exhibited LARR. The plasma corin concentrations drawn pre- and post-procedure in the LARR group were 442.85 [241.25, 631.68] and 516.83 [362.4,697.84] pg/mL, and those were significantly higher than those in the non-LARR group (393.82 [207.09, 558.11] and 473.77 [320.88, 665.75] pg/mL; Conclusions: Although plasma corin concentrations were increased in the LARR group, it provided minimal prognostic utility in LARR after CA of AF.

Indexed as

Atrial FibrillationAtrial RemodelingCatheter AblationSerine EndopeptidasesAgedBiomarkersFemaleFollow-Up StudiesHumansMaleMiddle AgedPrognosisProspective StudiesBiomarkersCORIN protein, humanSerine Endopeptidasesatrial fibrillationcatheter ablationcorinleft atrial reverse remodelingleft atrial volume index

Identifiers

PMID41367914
PMCPMC12682628

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.