Evidence map›Paper›PMID 41367904›Full record

ReviewBioscience2025

Evolvability: progress and key questions.

Christophe Pélabon, Gustavo A Agudelo-Cantero, Yimen G Araya Ajoy, Geir H Bolstad, Changde Cheng, Frietson Galis, Frederic Guillaume, Thomas R Haaland, Benedikt Hallgrímsson, Thomas F Hansen and 16 more

Abstract readReview
In one paragraph

Review in Bioscience, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Nucleotide diversity is a poor predictor of short-term adaptive potential.Proceedings of the National Academy of Sciences of the United States of America · 2026
    Article
  3. Bridging developmental and statistical approaches to variation and evolution.Proceedings of the National Academy of Sciences of the United States of America · 2026
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

26 authors.

Christophe PélabonDepartment of Biology, Norwegian University of Science and Technology, Trondheim, Norway.ORCID https://orcid.org/0000-0002-8630-8983
Gustavo A Agudelo-CanteroCentre for Ecological and Evolutionary Synthesis, Department of Biosciences, University of Oslo, Blindern, Oslo, Norway.
Yimen G Araya AjoyDepartment of Biology, Norwegian University of Science and Technology, Trondheim, Norway.
Geir H BolstadNorwegian Institute for Nature Research, Trondheim, Norway.ORCID https://orcid.org/0000-0003-1356-8239
Changde ChengDepartment of Medicine, Stem Cell Program, Department of Biomedical Informatics and Data Science, University of Alabama, Birmingham, Alabama, United States.ORCID https://orcid.org/0000-0002-2458-2522
Frietson GalisNaturalis Biodiversity Center, Leiden, Netherlands.
Frederic GuillaumeOrganismal and Evolutionary Biology Research Program, University of Helsinki, Helsinki, Finland.
Thomas R HaalandDepartment of Biology, Norwegian University of Science and Technology, Trondheim, Norway.ORCID https://orcid.org/0000-0002-6968-4514
Benedikt HallgrímssonDepartment of Cell Biology and Anatomy, University of Calgary, Calgary, Alberta, Canada.ORCID https://orcid.org/0000-0002-7192-9103
Thomas F HansenCentre for Ecological and Evolutionary Synthesis, Department of Biosciences, University of Oslo, Blindern, Oslo, Norway.
Agnes HolstadDepartment of Biology, Norwegian University of Science and Technology, Trondheim, Norway.ORCID https://orcid.org/0000-0003-3154-1857
David HouleDepartment of Biological Science, Florida State University, Tallahassee, Florida, United States.ORCID https://orcid.org/0000-0002-8095-3156
Gene HuntDepartment of Paleobiology, National Museum of Natural History, Smithsonian Institution, Washington, DC, United States.ORCID https://orcid.org/0000-0001-6430-5020
Anders IsaksenCentre for Ecological and Evolutionary Synthesis, Department of Biosciences, University of Oslo, Blindern, Oslo, Norway.
Lisandro MiloccoDepartment of Zoology, SciLifeLab, Stockholm University, Stockholm, Sweden.
Naid MubaleghCentre for Ecological and Evolutionary Synthesis, Department of Biosciences, University of Oslo, Blindern, Oslo, Norway.
Laura Nuño de la RosaDepartment of Logic and Theoretical Philosophy, Complutense University of Madrid, Madrid, Spain.
Steven H OrzackFresh Pond Research Institute, Cambridge, Massachusetts, United States.
Arthur PortoFlorida Museum of Natural History, Department of Biology, University of Florida, Gainesville, Florida, United States.
Jane M ReidDepartment of Biology, Norwegian University of Science and Technology, Trondheim, Norway.
Jacqueline L SztepanaczDepartment of Ecology and Evolutionary Biology, University of Toronto, Toronto, Ontario, Canada.ORCID https://orcid.org/0000-0002-4962-0150
Eivind A B UndheimCentre for Ecological and Evolutionary Synthesis, Department of Biosciences, University of Oslo, Blindern, Oslo, Norway.
Cristina VillegasKonrad Lorenz Institute for Evolution and Cognition Research, Klosterneuburg, Austria.ORCID https://orcid.org/0000-0002-6402-5288
Kjetil L VojeNatural History Museum, University of Oslo, Oslo, Norway.ORCID https://orcid.org/0000-0003-2556-3080
Craig WallingInstitute of Ecology and Evolution, School of Biological Science, University of Edinburgh, Edinburgh, Scotland, United Kingdom.
Jonathan WrightDepartment of Biology, Norwegian University of Science and Technology, Trondheim, Norway.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Since the 1990s, evolutionary biologists have recognized the importance of explaining the ability of biological systems to evolve and how this ability itself evolves. This recognition of the need to explain evolvability emerged from an awareness that the kind and the amount of heritable variation available for natural selection require explanation. The concept of evolvability is now the focus of many research programs in diverse subdisciplines within evolutionary biology. In the present article, we first review and synthesise progress made in evolvability research. We then present key questions to set an agenda for future research on evolvability, identify challenges to answer these questions, and discuss opportunities to apply results from the evolvability research to conservation biology.

Indexed as

evo-devoevolutionary quantitative geneticsevolutionary systems biologyevolvabilitypaleobiology

Identifiers

PMID41367904
PMCPMC12683529

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.