Evidence map›Paper›PMID 41367893›Full record

ReviewInternational journal of general medicine2025

The Oral Microbiota and Its Implications for Inflammatory Bowel Disease: A Literature Review.

Xiao-Kai Chen, Tao Mao, Xiang Song, Lin-Lin Ren

Abstract readReview
In one paragraph

Review in International journal of general medicine, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Xiao-Kai Chen *Department of Gastroenterology, Affiliated Hospital of Qingdao University, Qingdao, Shandong, 266000, People's Republic of China.
Tao Mao *Department of Gastroenterology, Affiliated Hospital of Qingdao University, Qingdao, Shandong, 266000, People's Republic of China.
Xiang Song *Department of Gastroenterology, Affiliated Hospital of Qingdao University, Qingdao, Shandong, 266000, People's Republic of China.
Lin-Lin Ren *Department of Gastroenterology, Affiliated Hospital of Qingdao University, Qingdao, Shandong, 266000, People's Republic of China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundInflammatory bowel disease (IBD) encompasses Crohn's disease (CD) and ulcerative colitis (UC) and represents a heterogeneous spectrum of chronic intestinal inflammation with no exclusive etiology. Emerging evidence underscores that IBD arises from complex interactions between host factors and microbial communities. The disruption of microbial homeostasis facilitates the colonization and invasion of opportunistic pathogens within the gut, precipitating an exaggerated host immune response and driving disease progression. While extensive research has elucidated the role of the gut microbiota in IBD pathogenesis, the contribution of the oral microbiota to this process is garnering increasing attention. Oral microbes can translocate to the intestine via the swallowing of saliva, and harmful oral bacteria and proinflammatory immune cells from the oral mucosa may migrate to the gut, eliciting immune activation. This review explores the emerging role of the oral microbiota in IBD pathogenesis and synthesizes recent advancements in understanding the intricate relationship between oral microbial communities and IBD.

Indexed as

dysbiosisimpaired intestinal barrier functionmicrobial translocationoral-gut axis

Identifiers

PMID41367893
PMCPMC12683014

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.