ArticleQuantitative imaging in medicine and surgery2025
The impact of baseline right ventricular-pulmonary artery coupling on the short-term outcome after valve replacement surgery for rheumatic mitral stenosis.
Article in Quantitative imaging in medicine and surgery, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
Background: Right ventricular dysfunction (RVD) signals poor prognosis in mitral valve replacement (MVR) patients. Right ventricular-pulmonary artery (RV-PA) coupling reflects how efficiently RV stroke work transfers to the pulmonary artery. This study evaluated the effect of RVD (due to impaired RV-PA coupling) on the short-term prognosis of rheumatic mitral stenosis (RMS) patients post-MVR. Methods: RV-PA coupling parameters were calculated by the ratio of tricuspid annular plane systolic excursion/pulmonary artery systolic pressure (TAPSE/PASP) from transthoracic echocardiography. The characteristics and outcomes of RMS patients with MVR were compared according to the TAPSE/PASP ratio. The primary outcome was 90-day mortality, and the secondary outcome was perioperative adverse events. Results: A total of 286 RMS patients were finally included, 112 patients had RVD (39.2% TAPSE/PASP ≤0.32 mm/mmHg). RVD patients showed higher 90-day mortality (16.1% Conclusions: Impaired baseline RV-PA coupling predicts poor outcomes in RMS patients undergoing MVR. Echocardiography is valuable for RMS severity assessment, particularly for overlooked severe RMS cases with mild PH.
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