ArticleQuantitative imaging in medicine and surgery2025
CMR-based left atrial strain for predicting left ventricular diastolic dysfunction in asymptomatic hypertensive patients.
Article in Quantitative imaging in medicine and surgery, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
1 citing paper in PubMed.
- Left Atrial Reservoir Strain Combined With Left Ventricular Longitudinal Strain Improves Discrimination of HFpEF in Patients With Hypertension.Journal of clinical hypertension (Greenwich, Conn.) · 2026Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Background: Left ventricular diastolic dysfunction (LVDD) is highly prevalent in hypertension (HTN) and is strongly associated with heart failure with preserved ejection fraction (HFpEF). However, conventional cardiac magnetic resonance (CMR) protocols lack guideline-recommended hemodynamic parameters for diastolic function assessment, thereby limiting their utility in LVDD evaluation. This study employed CMR feature tracking (CMR-FT) to analyze left atrial (LA) function in patients with subclinical HTN. We aimed to validate CMR-FT-derived LA strain as a marker for detecting LVDD with elevated left atrial pressure (LAP), thereby providing CMR parameters for diastolic dysfunction evaluation without additional scanning. Methods: This retrospective study included 152 HTN patients and 60 healthy controls who underwent echocardiography and CMR. According to guidelines, patients with HTN were stratified into the HTN with normal LAP group (no LVDD or grade I LVDD) and the HTN with elevated LAP group (grade II or higher LVDD). LA strain parameters reflecting phasic functions (reservoir, conduit, and pump) were quantified with CMR-FT. Intergroup differences in left ventricular (LV) functional parameters and LA strain were compared using ANOVA, Kruskal-Wallis, or Chi-squared tests. Independent correlations of LA strain were identified by multivariable linear regression. The diagnostic performance of LA parameters for elevated LAP was evaluated by generating receiver operating characteristic (ROC) curves. Results: Compared to healthy controls, both HTN (normal LAP) and HTN (elevated LAP) groups exhibited significant impairment in LA reservoir strain (εs: 33.90%±5.51% and 24.75%±4.91% Conclusions: CMR-derived LA strain demonstrates high discriminatory power for cardiac impairment in HTN patients, serving as a sensitive marker for LVDD with elevated LAP. LA strain and LAVmin show strong potential as clinically applicable parameters for routine diastolic function assessment in CMR.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.