ArticleQuantitative imaging in medicine and surgery2025
Shock index, modified shock index, and age-adjusted shock index for the prediction of impaired myocardial work in patients with ST-segment elevation myocardial infarction.
Article in Quantitative imaging in medicine and surgery, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
Background: The association between shock index (SI) and myocardial work indices has not been well characterized. This study aimed to validate the value of SI and its variants [modified shock index (MSI) and age-adjusted shock index (ASI)] for predicting myocardial work impairment in patients with ST-segment elevation myocardial infarction (STEMI). Methods: Left ventricular two-dimensional speckle-tracking echocardiography was performed in 37 patients with STEMI and in 37 age-, sex, and cardiovascular risk factor-matched controls. Left ventricular global longitudinal strain (GLS), global work index (GWI), global constructive work (GCW), global wasted work, and global work efficiency (GWE) were acquired. In males, impaired myocardial work was defined as follows: GLS >-16%, GWI <1,270 mmHg%, GCW <1,650 mmHg%, global wasted work >238 mmHg%, and GWE <90%; meanwhile, in females, it was defined as GLS >-16%, GWI <1,310 mmHg%, GCW <1,544 mmHg%, global wasted work >239 mmHg%, and GWE <91%. Results: Patients with STEMI, as compared with controls, demonstrated significantly lower GWI (1,258.53±492.83 Conclusions: The SI and MSI outperform ASI at predicting myocardial work impairment (GWI and GCW) in patients with STEMI. Clinically, the SI or MSI should be prioritized for early risk assessment.
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