ArticleQuantitative imaging in medicine and surgery2025
Optimizing computed tomography enterography with virtual monoenergetic imaging of second-generation dual-layer spectral CT in inflammatory bowel disease.
Article in Quantitative imaging in medicine and surgery, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
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7 authors.
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Abstract
Background: Second-generation dual-layer spectral computed tomography enterography (DLCTE) provides advanced virtual monoenergetic imaging (VMI) that may overcome conventional computed tomography (CT) enterography limitations in inflammatory bowel disease (IBD). This study aimed to identify the optimal VMI energy level in spectral CT enterography for IBD using quantitative and qualitative image quality assessments. Methods: This case-control study retrospectively analyzed 44 patients with endoscopically confirmed active IBD undergoing DLCTE. Conventional polyenergetic images (PEIs) and VMIs (40-100 keV, 10-keV increments) were reconstructed across non-contrast, arterial, and venous phases. Quantitative metrics [contrast-to-noise ratio (CNR), signal-to-noise ratio (SNR), CT attenuation, image noise] and subjective image quality (5-point Likert scale) were compared between PEIs and VMIs. Results: Quantitative analysis revealed that VMI 40 keV achieved peak performance: highest CT attenuation values (AV) [non-contrast: 57.7±13.2 Hounsfield units (HU) Conclusions: The dual-layer detector spectral CT low-level VMI can optimize the image quality of CTE in IBD, and is useful to evaluate the intestinal inflammatory range. Among them, the VMI 60 keV imaging has the best display and can increase the diagnostic confidence in active IBD, and it is suitable for clinical promotion and use.
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