Evidence map›Paper›PMID 41367667›Full record

ArticleERJ open research2025

Airflow obstruction among young adults in Europe: a Chronic Airway Diseases Early Stratification (CADSET) collaboration with 48 612 individuals across eight population-based cohorts.

Yunus Çolak, James P Allinson, Maarten van den Berge, Debbie Jarvis, Arnulf Langhammer, Robab Breyer-Kohansal, Bright I Nwaru, Helena Backman, Judith M Vonk, Børge G Nordestgaard and 13 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in ERJ open research, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

23 authors.

Yunus ÇolakDepartment of Respiratory Medicine, Copenhagen University Hospital - Herlev and Gentofte, Copenhagen, Denmark.ORCID https://orcid.org/0000-0003-2045-829X
James P AllinsonRoyal Brompton and Harefield NHS Foundation Trust, London, UK.
Maarten van den BergeDepartment of Pulmonary Diseases, University of Groningen, University Medical Center Groningen, Groningen, the Netherlands.
Debbie JarvisNational Heart and Lung Institute, Imperial College London, London, UK.ORCID https://orcid.org/0000-0002-1753-3896
Arnulf LanghammerHUNT Research Centre, Department of Public Health and Nursing, Faculty of Medicine and Health Sciences, NTNU, Levanger, Norway.ORCID https://orcid.org/0000-0001-5296-6673
Robab Breyer-KohansalLudwig Boltzmann Institute for Lung Health, Vienna, Austria.
Bright I NwaruKrefting Research Centre, Institute of Medicine, University of Gothenburg, Gothenburg, Sweden.
Helena BackmanDepartment of Public Health and Clinical Medicine, Umea University, Umea, Sweden.ORCID https://orcid.org/0000-0002-0553-8067
Judith M VonkGroningen Research Institute for Asthma and COPD, University of Groningen, University Medical Center Groningen, Groningen, the Netherlands.ORCID https://orcid.org/0000-0001-7531-4547
Børge G NordestgaardDepartment of Clinical Medicine, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark.
Peter LangeDepartment of Respiratory Medicine, Copenhagen University Hospital - Herlev and Gentofte, Copenhagen, Denmark.
Sigrid A Aalberg VikjordHUNT Research Centre, Department of Public Health and Nursing, Faculty of Medicine and Health Sciences, NTNU, Levanger, Norway.ORCID https://orcid.org/0000-0002-7202-4517
Marie-Kathrin BreyerLudwig Boltzmann Institute for Lung Health, Vienna, Austria.
Hannu KankaanrantaKrefting Research Centre, Department of Internal Medicine and Clinical Nutrition, Institute of Medicine, Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden.
Anne LindbergDepartment of Public Health and Clinical Medicine, Umea University, Umea, Sweden.ORCID https://orcid.org/0000-0002-3292-7471
Eva RönmarkDepartment of Public Health and Clinical Medicine, Section of Sustainable Health/the OLIN unit, Umea University, Umea, Sweden.ORCID https://orcid.org/0000-0002-2358-8754
Lowie E G W VanfleterenCOPD Centre, Department of Respiratory Medicine and Allergology, Sahlgrenska University Hospital, Gothenburg, Sweden.ORCID https://orcid.org/0000-0002-4387-4096
Jørgen VestboDivision of Infection, Immunity and Respiratory Medicine, School of Biological Sciences, Manchester Academic Health Science Centre, University of Manchester, Manchester, United Kingdom.ORCID https://orcid.org/0000-0001-6355-6362
Jadwiga A WedzichaNational Heart and Lung Institute, Imperial College London, London, UK.
Erik MelénDepartment of Clinical Science and Education Södersjukhuset, Karolinska Institutet and Sachs' Children and Youth Hospital, Stockholm, Sweden.ORCID https://orcid.org/0000-0002-8248-0663
Alvar AgustíCatedra Salut Respiratoria, University of Barcelona, Respiratory Institute, Hospital Clinic, IDIBAPS, CIBERES, Barcelona, Spain.ORCID https://orcid.org/0000-0003-3271-3788
Rosa FanerUniversitat de Barcelona, Centro de Investigación Biomedica en Red Enfermedades Respiratorias, Fundació Clinic Recerca Biomedica-IDIBAPS-Hospital Clinic de Barcelona, Barcelona, Spain.
Shoaib AfzalDepartment of Clinical Medicine, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark.ORCID https://orcid.org/0000-0002-1442-4694

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: The extent to which airflow obstruction, a key feature of COPD, can be already present in early adulthood is unclear. We investigated the prevalence of airflow obstruction in young adults across European populations. Methods: We identified 48 612 individuals aged 20-40 years across eight population-based European cohorts in the Chronic Airway Diseases Early Stratification (CADSET) collaboration and applied two commonly used definitions of airflow obstruction: pre-bronchodilator forced expiratory volume in 1 s (FEV Results: Airflow obstruction prevalence increased with increasing age from 2.3% in those aged 20-24.9 years to 6.3% in those aged 35-39.9 years according to FEV Conclusion: Up to 8% of young adults across Europe have airflow obstruction; its cause and its role in prior, concurrent and future airway disease merit further investigation.

Identifiers

PMID41367667
PMCPMC12683578

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.