Evidence map›Paper›PMID 41367659›Full record

ArticleERJ open research2025

Bronchial rheoplasty for chronic bronchitis: real-world evidence of safety and performance.

Judith Brock, Felix Herth, Kaid Darwiche, Ralf-Harto Hübner, Dirk Skowasch, Björn Schwick, Wolfgang Gesierich, Christian Schumann, Arschang Valipour

Abstract read
In one paragraph

Article in ERJ open research, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Review
  2. Article
  3. Article
  4. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Judith BrockDepartment for Pneumology and Critical Care Medicine, Thoraxklinik, University of Heidelberg, Heidelberg, Germany.
Felix HerthDepartment for Pneumology and Critical Care Medicine, Thoraxklinik, University of Heidelberg, Heidelberg, Germany.ORCID https://orcid.org/0000-0002-7638-2506
Kaid DarwicheDepartment for Interventional Pneumology, Ruhrlandklinik - University Medicine, Essen, Germany.ORCID https://orcid.org/0000-0003-0681-1325
Ralf-Harto HübnerDepartment of Infectious Diseases, Respiratory Medicine and Critical Care, Charité-Universitätsmedizin Berlin, Berlin, Germany.
Dirk SkowaschDepartment of Internal Medicine II - Pneumology, University of Bonn, Bonn, Germany.
Björn SchwickDepartment of Pneumology, Luisenhospital Aachen, Aachen, Germany.
Wolfgang GesierichAsklepios-Fachkliniken München Gauting, Gauting, Germany.ORCID https://orcid.org/0000-0001-6707-6358
Christian SchumannClinic of Pneumology, Thoracic Oncology, Sleep and Respiratory Critical Care, Kempten and Immenstadt, Germany.ORCID https://orcid.org/0000-0001-8143-5978
Arschang ValipourKarl-Landsteiner-Institute for Lung Research, Department of Respiratory and Critical Care Medicine, Klinik Floridsdorf, Vienna, Austria.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Bronchial rheoplasty (BR) addresses mucosal inflammation and hypersecretion associated with chronic bronchitis (CB) by ablating goblet cell hyperplasia with nonthermal pulsed electric fields. This study assessed if BR continues to demonstrate a safe profile and symptom burden reduction in CB patients. Methods: This observational, post-market, single-arm registry was conducted at eight centres in Austria and Germany. Patients with CB and high symptom burden (COPD assessment test (CAT) score ≥7 points in the first two questions) were treated with two bronchoscopic BR procedures. The primary outcomes were safety and symptom burden at 12 months, evaluated by (serious) adverse events ((S)AEs) and questionnaire scores (CAT and St. George's Respiratory Questionnaire (SGRQ)). Subgroup analyses were performed to identify treatment responders. Results: 106 BR procedures were performed in 54 patients (mean forced expiratory volume in 1 s (FEV Conclusion: The real-world clinical experience demonstrates that BR is a relatively safe and promising treatment option for CB patients with significant symptom burden.

Identifiers

PMID41367659
PMCPMC12683551

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.