ArticleERJ open research2025
Non-pharmacological interventions for inducible laryngeal obstruction: a thematic analysis towards a standardised approach.
Article in ERJ open research, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
1 citing paper in PubMed, 1 synthesis or guideline pooled it.
- Upper Airway Control Therapy (U-ACT): The Development of a Non-Pharmacological Intervention for Inducible Laryngeal Obstruction.Respirology (Carlton, Vic.) · 2025Pooled it
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Background: Non-pharmacological treatment is recommended for inducible laryngeal obstruction (ILO) but evidence for effectiveness is limited. A standardised approach does not exist and there are many key uncertainties for intervention delivery. The aims of the present study were to identify, from patients and speech and language therapists (SLTs), what the key considerations and components are for a standardised non-pharmacological intervention for ILO. Methods: Qualitative data were collected during a SLT focus group and one-to-one patient semistructured interviews (SLTs (n=7); intervention-naïve patients (n=6); patients who had received a non-pharmacological intervention aimed to control ILO (n=16)). A Framework Method analysis was conducted to explore and identify themes in the data. Results: SLTs were very experienced (median (interquartile range; range) 19 (13; 6-34) years post-qualification and 7 (3; 4-25) years of holding a weekly ILO caseload). Patients were predominantly female (73%) with mean±sd age 53±13 years. Patient participants expressed a fear of ILO and unanimous support for an intervention. Five main themes were identified: 1) "Living with ILO" highlighted rationale and motivation; 2) "Pathway to intervention" offered understanding on the wider context related to access; 3) "Care delivery" answered important key uncertainties relating to intervention implementation; 4) "Intervention components" detailed specific components; and 5) "Views of interventions" identified mediators of change. All interviewees deemed a standardised non-pharmacological approach would be highly desirable to help improve patient outcomes. Conclusion: This work provides evidence, from key stakeholders, on the fundamentals for a non-pharmacological ILO intervention. It will inform future work to establish a standardised approach worthy of a formal evaluation of effectiveness.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.