Trajectories of cumulative fluid balance and the association with pressure injuries in ICU patients.

Xiangping Chen, Peiqi Liu, Bingyan Zhu, Xiumin Qiu, Wei Yu, Yuewen Lao, Xiaoyan Gong, Yiyu Zhuang

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Article in International journal of nursing sciences, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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8 authors.

Xiangping ChenNursing Department, Sir Run Run Shaw Hospital, Zhejiang University School of Medicine, Hangzhou, China.

Peiqi LiuNursing Department, Sir Run Run Shaw Hospital, Zhejiang University School of Medicine, Hangzhou, China.

Bingyan ZhuNursing Department, Sir Run Run Shaw Hospital, Zhejiang University School of Medicine, Hangzhou, China.

Xiumin QiuNursing Department, Sir Run Run Shaw Hospital, Zhejiang University School of Medicine, Hangzhou, China.

Wei YuNursing Department, Sir Run Run Shaw Hospital, Zhejiang University School of Medicine, Hangzhou, China.

Yuewen LaoNursing Department, Sir Run Run Shaw Hospital, Zhejiang University School of Medicine, Hangzhou, China.

Xiaoyan GongNursing Department, Sir Run Run Shaw Hospital, Zhejiang University School of Medicine, Hangzhou, China.

Yiyu ZhuangNursing Department, Sir Run Run Shaw Hospital, Zhejiang University School of Medicine, Hangzhou, China.

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6 · The paper itself

Abstract

Objective: This study aimed to investigate the longitudinal trajectories of cumulative fluid balance (CFB) in intensive care unit (ICU) patients and analyze the relationship between different trajectory groups and the occurrence of pressure injuries (PIs). Methods: In this retrospective longitudinal study, we obtained health-related data from the Medical Information Mart for Intensive Care IV database, including sociodemographic, disease-related variables, and ICU treatment variables. The daily CFB adjusted for body weight was calculated, and the occurrence of PIs during the ICU stay was recorded. A group-based trajectory model was used to explore the different CFB trajectories. Binary logistic regression was used to analyze the relationship between the CFB trajectory group and PIs. Results: Among the 4,294 included participants, we identified four distinct trajectories of CFB in ICU patients: the rapid accumulation group (12.5 %), the slow accumulation group (28.5 %), the neutral balance group (41.7 %), and the negative decrease group (17.3 %). After adjusting for some sociodemographic, disease-related variables, and ICU treatment variables, the rapid accumulation group had an Conclusions: Four unique trajectories of CFB were identified among patients in the ICU, including rapid accumulation, slow accumulation, neutral balance, and negative decrease. Rapid accumulation independently increased the risk of PIs during ICU stay.

Indexed as

Cumulative fluid balanceFluid overloadIntensive care unitPressure injuryTrajectory

Identifiers

PMID41367596

DOI10.1016/j.ijnss.2025.10.004

PMCPMC12684758

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