ReviewDiabetes, metabolic syndrome and obesity : targets and therapy2025
The Association Between Diabetes Mellitus and Perianal Abscess: A Meta-Analysis.
Review in Diabetes, metabolic syndrome and obesity : targets and therapy, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
1 citing paper in PubMed.
- Impact of diabetes mellitus and glycemic control on postoperative recurrence of perianal abscess: a retrospective, single-center study.Frontiers in medicine · 2026Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Introduction: Perianal abscess (PA), a common anorectal emergency, affects approximately 2-3% of the global population. Increasing evidence indicates a relationship between PA and metabolic disorders. Considering the anticipated rise in diabetes mellitus (DM) cases to 1 billion worldwide by 2045, clarifying the epidemiological association and clinical characteristics linking glucose dysregulation with PA holds considerable clinical importance. Purpose: This study aimed to elucidate the bidirectional epidemiological relationship between DM and PA and to define their respective clinical profiles, thereby contributing to risk stratification and optimization of management strategies. Methods: Observational studies examining the association between DM and PA were systematically retrieved from PubMed, EMBASE, Cochrane Library, CNKI, Wanfang, and VIP databases (from inception to November 2024). Two independent reviewers conducted study selection, data extraction, and quality assessment using the Newcastle-Ottawa Scale. Random-effects models were applied to calculate pooled prevalence, odds ratios (OR), relative risks (RR), and 95% confidence intervals (CI). Heterogeneity, sensitivity, and publication bias were evaluated using Cochran's Q test, I Results: The meta-analysis demonstrated a strong bidirectional association between DM and PA, with 30.7% of PA cases occurring in patients with DM and 22.0% of individuals with DM developing PA. Male sex conferred a significantly higher risk (OR=15.00, 95% CI: 7.87-28.59). DM was linked to altered microbial profiles-lower prevalence of Escherichia coli (OR=0.57, 95% CI: 0.39-0.84) and higher detection of Conclusion: The interrelationship between DM and PA is characterized by mutual risk amplification and distinct clinical manifestations, including sex-related vulnerability, microbial alterations, and poorer prognostic outcomes. These findings indicate the necessity for individualized antimicrobial regimens and enhanced postoperative monitoring in patients with DM.
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