Evidence map›Paper›PMID 41367518›Full record

ArticleTranslational pediatrics2025

Effectiveness of surfactant treatment and retreatment in moderately preterm infants.

Carlo Dani, Simone Pratesi, Giulia Inguscio, Alessia Bonetti, Lara Devilli, Alessia Rizzello, Ginevra Prelazzi, Greta Mariani, Iuri Corsini

Abstract read
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In one paragraph

Article in Translational pediatrics, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Carlo DaniDepartment of Neurosciences, Psychology, Drug Research and Child Health, University of Florence, Florence, Italy.
Simone PratesiDepartment of Neurosciences, Psychology, Drug Research and Child Health, University of Florence, Florence, Italy.
Giulia InguscioDepartment of Neurosciences, Psychology, Drug Research and Child Health, University of Florence, Florence, Italy.
Alessia BonettiDepartment of Neurosciences, Psychology, Drug Research and Child Health, University of Florence, Florence, Italy.
Lara DevilliDepartment of Neurosciences, Psychology, Drug Research and Child Health, University of Florence, Florence, Italy.
Alessia RizzelloDepartment of Neurosciences, Psychology, Drug Research and Child Health, University of Florence, Florence, Italy.
Ginevra PrelazziDepartment of Neurosciences, Psychology, Drug Research and Child Health, University of Florence, Florence, Italy.
Greta MarianiDepartment of Neurosciences, Psychology, Drug Research and Child Health, University of Florence, Florence, Italy.
Iuri CorsiniDepartment of Neurosciences, Psychology, Drug Research and Child Health, University of Florence, Florence, Italy.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Respiratory distress syndrome (RDS) is commonly treated in preterm infants with surfactant and artificial respiratory support. However, their effects have been demonstrated in infants born before 30 weeks of gestational age, while there are no data on the efficacy of surfactant treatment and retreatment in the subgroup of moderately preterm infants (MPIs). We aimed to assess changes in oxygenation indices and RDS severity after surfactant administration in MPIs and to identify possible risk factors for the need for multiple doses of surfactant in these patients. Methods: We conducted a retrospective study on 60 MPIs born between 30 Results: A total of 48 infants (80%) received a single dose of surfactant, while 12 infants (20%) received multiple doses. Both the SpO Conclusions: The first and second doses of surfactant improved the oxygenation indices and reduced the severity of RDS in MPIs. The post-surfactant SpO

Indexed as

multiple dosespreterm infantrespiratory distress syndrome (RDS)Surfactant

Identifiers

PMID41367518
PMCPMC12683493

What OpenQuestion holds

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LicenceCC BY-NC-ND
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.