Evidence map›Paper›PMID 41367411›Full record

ArticleCase reports in critical care2025

Acute Massive Hydroxychloroquine Overdose of 60 g in an Adult, Successfully Resuscitated: A Successful Salvage.

Archit Vora, Anselm Wong, Alastair Brown

Abstract read
In one paragraph

Article in Case reports in critical care, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Archit VoraDepartment of Critical Care, Intensive Care Unit, St. Vincent's Hospital, Melbourne, Australia, cmcvincent.or.kr.ORCID https://orcid.org/0009-0008-6259-1033
Anselm WongVictorian Poisons Centre and Austin Toxicology Unit, Melbourne, Australia.ORCID https://orcid.org/0000-0002-6817-7289
Alastair BrownDepartment of Critical Care, Intensive Care Unit, St. Vincent's Hospital, Melbourne, Australia, cmcvincent.or.kr.ORCID https://orcid.org/0000-0002-3137-4895

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

We present the case of a 29-year-old female who ingested a 60 g dose of hydroxychloroquine in a suicide attempt. This report details the acute clinical presentation, successful management strategies, and prolonged sequelae of severe hydroxychloroquine toxicity, including recurrent and delayed episodes of Torsades de Pointes (TdP) and profound metabolic derangements. Early recognition, intensive supportive care, and the use of targeted interventions-including activated charcoal administration, meticulous electrolyte correction, and vasoactive support-were critical to successful management. This case underscores the importance of prompt intervention in hydroxychloroquine overdoses and provides a review of the pathophysiology and therapeutic strategies informed by current literature and our clinical experience.

Identifiers

PMID41367411
PMCPMC12683071

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.