Evidence map›Paper›PMID 41367391›Full record

ArticleFrontiers in physiology2025

Long-term multicomponent exercise enhances functional mobility in early-stage Parkinson's disease: a 48-month retrospective cohort study.

Marcos Moura, Marina Lívia Venturini Ferreira, Filipe Duo Speri, Lucas Celsius Matos Alves, João Vitor Cerávolo Rostirola, Edevaldo Donizetti de Campos, Miguel S Conceição

Abstract read
In one paragraph

Article in Frontiers in physiology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Marcos Moura *Health Science Program, Sao Francisco University, Bragança Paulista, Brazil.
Marina Lívia Venturini Ferreira *Health Science Program, Sao Francisco University, Bragança Paulista, Brazil.
Filipe Duo SperiHealth Science Program, Sao Francisco University, Bragança Paulista, Brazil.
Lucas Celsius Matos AlvesHealth Science Program, Sao Francisco University, Bragança Paulista, Brazil.
João Vitor Cerávolo RostirolaHealth Science Program, Sao Francisco University, Bragança Paulista, Brazil.
Edevaldo Donizetti de CamposVirtual University of the State of São Paulo, São Paulo, Brazil.
Miguel S ConceiçãoHealth Science Program, Sao Francisco University, Bragança Paulista, Brazil.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Long-term effects of structured exercise on functional capacity in Parkinson's disease (PD) remain poorly understood. Objective: To investigate the impact of a 48-month multicomponent exercise program on mobility, aerobic capacity, and muscle mass in individuals with early-stage PD, and to examine baseline predictors of functional performance. Methods: Thirty-three patients with PD (Hoehn & Yahr stages 1-2) participated in a supervised, thrice-weekly program including aerobic, resistance, balance, and flexibility exercises. Assessments at baseline and 48 months included the Timed Up and Go (TUG), Six-Minute Walk Test (6MWT), peak oxygen uptake (VO Results: After 48 months, TUG time decreased by -3.8 s (95% CI: -5.0 to -2.6; Conclusion: Long-term engagement in a multicomponent exercise program produces

Indexed as

exercise therapyfunctional mobilityParkinson’s diseaseTC6TUG

Identifiers

PMID41367391
PMCPMC12682783

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.