Evidence map›Paper›PMID 41367353›Full record

ArticleJournal of medicinal chemistry2025

Nanoscale Direct-to-Biology Optimization and Structural Insights into Selective

Ariane F Hübner, Annabelle C Weldert, Tessa Marciniak, Florian Hof, Vivien S Beck, Samuel Carien, Sophie N Mulartschyk, Eva Wolf, Wilma Ziebuhr, Fabian Barthels

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of medicinal chemistry, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Ariane F HübnerInstitute of Pharmaceutical and Biomedical Sciences, Johannes Gutenberg-University, Staudingerweg 5, 55128 Mainz, Germany.
Annabelle C WeldertInstitute of Pharmaceutical and Biomedical Sciences, Johannes Gutenberg-University, Staudingerweg 5, 55128 Mainz, Germany.ORCID 0009-0001-5016-0286
Tessa MarciniakInstitute of Molecular Infection Biology, University of Würzburg, Josef-Schneider-Strasse 2, 97080 Würzburg, Germany.
Florian HofInstitute of Molecular Physiology, Johannes Gutenberg-University, Hanns-Dieter-Hüsch-Weg 17, 55128 Mainz, Germany.ORCID 0000-0002-6438-1784
Vivien S BeckInstitute of Molecular Infection Biology, University of Würzburg, Josef-Schneider-Strasse 2, 97080 Würzburg, Germany.
Samuel CarienInstitute of Molecular Infection Biology, University of Würzburg, Josef-Schneider-Strasse 2, 97080 Würzburg, Germany.
Sophie N MulartschykInstitute of Pharmaceutical and Biomedical Sciences, Johannes Gutenberg-University, Staudingerweg 5, 55128 Mainz, Germany.
Eva WolfInstitute of Molecular Physiology, Johannes Gutenberg-University, Hanns-Dieter-Hüsch-Weg 17, 55128 Mainz, Germany.
Wilma ZiebuhrInstitute of Molecular Infection Biology, University of Würzburg, Josef-Schneider-Strasse 2, 97080 Würzburg, Germany.
Fabian BarthelsInstitute of Pharmaceutical and Biomedical Sciences, Johannes Gutenberg-University, Staudingerweg 5, 55128 Mainz, Germany.ORCID 0000-0001-7950-2158

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The tRNA m

Indexed as

Anti-Bacterial AgentsBacterial ProteinsEnzyme InhibitorsMethyltransferasesStaphylococcus aureusAzidesCrystallography, X-RayMicrobial Sensitivity TestsModels, MolecularMolecular StructureStructure-Activity RelationshipAnti-Bacterial AgentsAzidesBacterial ProteinsEnzyme InhibitorsMethyltransferases

Identifiers

PMID41367353
PMCPMC12751012

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.