Evidence map›Paper›PMID 41367201›Full record

ArticleEuropean journal of immunology2025

IL-10- and IL-13-Biased T Cell Responses to SARS-CoV-2 Vaccination in Diabetes.

Emma M Jones, Caren Sourij, Martin Stradner, Peter Schlenke, Nazanin Sereban, Othmar Moser, Rachael Quinlan, Charlotte-Eve Short, Benjamin H L Harris, Michael Fertleman and 4 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in European journal of immunology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors.

Emma M JonesDepartment of Infectious Disease, Faculty of Medicine, Imperial College London, London, UK.
Caren SourijDivision of Cardiology, Medical University of Graz, Austria.
Martin StradnerDivision of Rheumatology and Immunology, Medical University of Graz, Austria.
Peter SchlenkeDepartment of Blood Group Serology and Transfusion Medicine, Medical University of Graz, Austria.
Nazanin SerebanDepartment of Blood Group Serology and Transfusion Medicine, Medical University of Graz, Austria.
Othmar MoserUniversity of Bayreuth, Bayreuth, Germany.
Rachael QuinlanDepartment of Infectious Disease, Faculty of Medicine, Imperial College London, London, UK.
Charlotte-Eve ShortDepartment of Infectious Disease, Faculty of Medicine, Imperial College London, London, UK.
Benjamin H L HarrisDepartment of Bioengineering, Faculty of Engineering, Imperial College London, London, UK.
Michael FertlemanDepartment of Bioengineering, Faculty of Engineering, Imperial College London, London, UK.
Graham P TaylorDepartment of Infectious Disease, Faculty of Medicine, Imperial College London, London, UK.
Nick OliverDepartment of Metabolism, Digestion and Reproduction, Faculty of Medicine, Imperial College London, London, UK.
Harald SourijInterdisciplinary Metabolic Medicine Trials Unit, Division of Endocrinology and Diabetology, Medical University of Graz, Austria.
Margarita Dominguez-VillarDepartment of Infectious Disease, Faculty of Medicine, Imperial College London, London, UK.

Funding

Austrian Science FundDiabetes UK
6 · The paper itself

Abstract

Type 1 and type 2 diabetes are associated with increased severity and mortality from respiratory virus infections. Vaccination in the general population significantly reduces the risk of severe respiratory viral infection and triggers a strong, polyfunctional, and lasting T cell response in healthy individuals. However, vaccine effectiveness in people with type 1 diabetes is unclear. Here, we studied the magnitude and functional characteristics of vaccine-specific CD4

Indexed as

CD4-Positive T-LymphocytesCD8-Positive T-LymphocytesCOVID-19COVID-19 VaccinesDiabetes Mellitus, Type 1Diabetes Mellitus, Type 2Interleukin-10Interleukin-13SARS-CoV-2AdultAgedFemaleHumansImmunologic MemoryMaleMiddle AgedCOVID-19 VaccinesIL10 protein, humanIL13 protein, humanInterleukin-10Interleukin-13diabetesmemorySARS‐CoV‐2T cellstype 1 diabetesvaccination

Identifiers

PMID41367201
PMCPMC12690275

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.