Evidence map›Paper›PMID 41367099›Full record

ArticleAngewandte Chemie (International ed. in English)2026

Novel Sulfonium Reagents for the Modular Synthesis of Spiro[2.3]Hexanes and Heteroatom-Containing Analogues: Synthesis, Application, and Evaluation as Bioisosteres.

Philipp Natho, Annarita Vicenti, Fabrizio Mastrolorito, Francesca De Franco, Lee Walsh-Benn, Marco Colella, Ernesto Mesto, Emanuela Schingaro, Orazio Nicolotti, Antimo Gioiello and 1 more

Abstract read
In one paragraph

Article in Angewandte Chemie (International ed. in English), 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Article
  2. Article
  3. Iron-Catalyzed Cyclopropanation of Allenes Using Unactivated Alkyl Sulfonium Salts.Angewandte Chemie (International ed. in English) · 2026
    Article
  4. Article
  5. Article
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Philipp NathoDepartment of Pharmacy-Drug Sciences, University of Bari "A. Moro", Via E. Orabona 4, Bari, 70125, Italy.
Annarita VicentiDepartment of Pharmacy-Drug Sciences, University of Bari "A. Moro", Via E. Orabona 4, Bari, 70125, Italy.
Fabrizio MastroloritoDepartment of Pharmacy-Drug Sciences, University of Bari "A. Moro", Via E. Orabona 4, Bari, 70125, Italy.
Francesca De FrancoTes Pharma S.r.l., Via Giovine Italia, 1, Solomeo, Corciano (PG), 06073, Italy.
Lee Walsh-BennCAS - A division of the American Chemical Society, ACS International, Ltd., 2540 Olentangy River Road, Columbus, Ohio, 43202, USA.
Marco ColellaDepartment of Pharmacy-Drug Sciences, University of Bari "A. Moro", Via E. Orabona 4, Bari, 70125, Italy.
Ernesto MestoDepartment of Earth and Geoenvironmental Sciences, University of Bari "A. Moro", Via E. Orabona 4, Bari, 70125, Italy.
Emanuela SchingaroDepartment of Earth and Geoenvironmental Sciences, University of Bari "A. Moro", Via E. Orabona 4, Bari, 70125, Italy.
Orazio NicolottiDepartment of Pharmacy-Drug Sciences, University of Bari "A. Moro", Via E. Orabona 4, Bari, 70125, Italy.
Antimo GioielloDepartment of Pharmaceutical Sciences, University of Perugia, Via del Liceo, 1, Perugia, 06123, Italy.
Renzo LuisiDepartment of Pharmacy-Drug Sciences, University of Bari "A. Moro", Via E. Orabona 4, Bari, 70125, Italy.ORCID https://orcid.org/0000-0002-9882-7908

Funding

European Commission Horizon Europe Framework, Project SusPharma 101057430European Commission's Horizon Europe, Project Expand Flow 101106497
6 · The paper itself

Abstract

Molecular scaffolds with a high fraction of sp

Indexed as

AzetidinesCyclobutanesHeterocyclesOxetanesSpiro[2.3]hexanesSulfonium saltsSynthetic methodologies

Identifiers

PMID41367099
PMCPMC12851011

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.