Evidence map›Paper›PMID 41367083›Full record

ArticleDrug testing and analysis2026

Further Insights Into the Metabolism of LGD-4033 in Human Urine. Part 1. Structure Elucidation of Additional Important Metabolites.

Yiannis S Angelis, Panagiotis Sakellariou, Mario Thevis, Andreas Thomas, Michael Petrou, Emmanuel N Pitsinos

Abstract read
In one paragraph

Article in Drug testing and analysis, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Yiannis S AngelisInstitute of Biosciences & Applications, National Centre for Scientific Research "DEMOKRITOS", Doping Control Laboratory of Athens, Athens, Greece.ORCID https://orcid.org/0000-0001-8773-1575
Panagiotis SakellariouInstitute of Biochemistry/Center for Preventive Doping Research, German Sport University Cologne, Cologne, Germany.
Mario ThevisInstitute of Biochemistry/Center for Preventive Doping Research, German Sport University Cologne, Cologne, Germany.ORCID https://orcid.org/0000-0002-1535-6451
Andreas ThomasInstitute of Biochemistry/Center for Preventive Doping Research, German Sport University Cologne, Cologne, Germany.ORCID https://orcid.org/0000-0003-1199-0743
Michael PetrouCyprus Anti-Doping Authority, Nicosia, Cyprus.
Emmanuel N PitsinosInstitute of Nanoscience and Nanotechnology, National Centre for Scientific Research "DEMOKRITOS", Athens, Greece.

Funding

World Anti-Doping Agency 21A17EP
6 · The paper itself

Abstract

This study presents LC-HRMS/MS analyses of LGD-4033 post-administration urine samples, following hydrolysis with β-glucuronidase and liquid-liquid extraction, against chemically synthesized molecules that matched previously proposed metabolites, characterized by

Indexed as

PyrrolidinonesChromatography, LiquidDoping in SportsHumansLiquid-Liquid ExtractionMagnetic Resonance SpectroscopyMaleSubstance Abuse DetectionTandem Mass SpectrometryPyrrolidinonesdopingLC‐HRMS/MSLGD‐4033 metabolismorganic synthesisstructure elucidation

Identifiers

PMID41367083
PMCPMC12861595

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.