SynthesisMedicine2025
Bruxism treatment outcomes: A systematic review and meta-analysis.
Synthesis in Medicine, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
2 citing papers in PubMed.
- Muscle Tone Regulation and Bruxism in Chronic Stress: Pathophysiological Links to Tooth Fractures and Dental Hard Tissue Pathology.Medical sciences (Basel, Switzerland) · 2026Review
- Influence of Prosthetic Material Properties and Implant Number on Stress Distribution in Implant-Bone Systems Under Bruxism Loading: A Finite Element Study.Biomimetics (Basel, Switzerland) · 2026Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
8 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundThis review aimed at addressing the treatment outcomes of bruxism.
methodsThe systematic review protocol was registered in International Prospective Register of Systematic Reviews with protocol number (CRD42024597809). It was conducted following the Preferred Reporting Items for Systematic Reviews and Meta-Analyses. The search was performed to retrieve the relevant articles from PubMed, Web of Science, and Scopus databases. The inclusion criteria were predefined as original studies including randomized and non-randomized controlled trials, case series, studies published between October 2019, and October 2024 published in English. The retrieved studies suitable for analysis were subjected for data extraction and risk of bias assessment using the Joanna Brigg Institute checklists for the relevant design of the studies.
resultsFinally, 22 studies were suitable for the data extraction and risk of bias assessment. Studies revealed that occlusal splints, both conventional and 3-dimensional-printed, have been widely studied for their ability to reduce nighttime muscle activity. These devices help distribute occlusal forces and alleviate symptoms, although their effectiveness varies depending on design and material. Botulinum toxin type A has been examined as a treatment option, particularly for reducing pain and muscle activity in patients with bruxism. Biofeedback devices have also been explored as a noninvasive alternative to control bruxism.
conclusionOverall, there is no single treatment that is universally effective for all patients. A multidisciplinary approach combining different therapies may yield the best results. Further long-term studies with rigorous methodological control are essential to evaluate the durability of therapeutic effects and determine the most cost-effective interventions.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.