Trial reportMedicine2025
The immediate effectiveness of a multi-channeled oral irrigator in reducing dental plaque and oral malodor: A preliminary single-blind clinical trial.
Trial report in Medicine, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
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Authors and funding
5 authors.
Funding
Abstract
backgroundThis study evaluated the immediate effectiveness of a multi-channeled oral irrigator (MCOI) in removing dental plaque and reducing oral malodor.
methodsIn 20 healthy volunteers, changes in dental plaque were assessed using the Patient Hygiene Performance index. Volatile sulfur compounds were measured before and immediately after a single use of the MCOI. Participants refrained from tooth brushing for 24 hours prior to the assessment. The device administered 1000 mL of water over a 1.5-minute cycle. Oral malodor was analyzed with gas chromatography focusing on methyl mercaptan (CH₃SH) and hydrogen sulfide. Statistical analysis was performed using the Wilcoxon signed-rank test and chi-square test.
resultsAfter a cycle of MCOI use, the average and divisions of the tooth Patient Hygiene Performance index scores significantly decreased (P < .001), with an average reduction of 24.76% in initial dental plaque. Additionally, total volatile sulfur compounds and CH₃SH concentrations significantly decreased (P = .011) after oral cleaning. Although the mean hydrogen sulfide concentrations decreased after oral cleaning, this change was not statistically significant (P = .088).
conclusionsTooth brushing typically removes approximately 42% to 60% of the initial dental plaque in healthy adults. A single cycle of MCOI use reduced plaque by approximately 25% and significantly lowered CH₃SH, a compound associated with periodontal disease. These findings suggest that the MCOI may serve as a useful adjunct to tooth brushing, particularly for individuals with limited motor skills, and could help reduce the risk of plaque-related oral diseases.
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