Evidence map›Paper›PMID 41366775›Full record

ArticleJournal of nanobiotechnology2025

Copper-coordinated engineered nanoreactors with self-amplifying O

Zhongxiong Fan, Lijun Ding, Fukai Zhu, Nan Yang, Yanrong Shi, Qian Sun, Jun Hai, Jinyao Li, Guanghao Su, Zhenqing Hou

Abstract read
In one paragraph

Article in Journal of nanobiotechnology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Zhongxiong Fan *School of Pharmaceutical Sciences, Institute of Materia Medica, Xinjiang University, Urumqi, 830017, China. fanzhongxiong@xju.edu.cn.ORCID http://orcid.org/0000-0001-5751-9530
Lijun Ding *School of Pharmaceutical Sciences, Institute of Materia Medica, Xinjiang University, Urumqi, 830017, China.
Fukai Zhu *School of Pharmaceutical Sciences, Institute of Materia Medica, Xinjiang University, Urumqi, 830017, China.
Nan YangSchool of Pharmaceutical Sciences, Institute of Materia Medica, Xinjiang University, Urumqi, 830017, China.
Yanrong ShiSchool of Pharmaceutical Sciences, Institute of Materia Medica, Xinjiang University, Urumqi, 830017, China.
Qian SunChildren's Hospital, Soochow University, Suzhou, 215025, China.
Jun HaiCAS Key Laboratory of Chemistry of Northwestern Plant Resources, Key Laboratory for Natural Medicine of Gansu Province, Lanzhou Institute of Chemical Physics, Chinese Academy of Sciences (CAS), Lanzhou, 730000, China. haijun@licp.cas.cn.ORCID http://orcid.org/0000-0002-7466-4649
Jinyao LiXinjiang Key Laboratory of Biological Resources and Genetic Engineering, College of Life Science and Technology, Xinjiang University, Urumqi, 830017, China. ljyxju@xju.edu.cn.ORCID http://orcid.org/0000-0002-3295-6096
Guanghao SuChildren's Hospital, Soochow University, Suzhou, 215025, China. sky2skeleton@163.com.
Zhenqing HouSchool of Pharmaceutical Sciences, Institute of Materia Medica, Xinjiang University, Urumqi, 830017, China.

Funding

Key Laboratory in Science and Technology Development Project of Suzhou (CN) SZS2024012Key research and development program in Xinjiang Uygur Autonomous Region 2023B02030-1National Natural Science Foundation of China 82560364Project of Jiangsu Province Key Research and Development Plan (Social Development) BE2022732
6 · The paper itself

Abstract

Efficient synthesis of chemotherapeutic drugs within the tumor microenvironment (TME) holds great potential for enhancing sonodynamic-mediated synergistic oncotherapy. Herein, an engineered nanoreactor composed of Cu

Indexed as

Antineoplastic AgentsCopperOxygenUltrasonic TherapyAnimalsCell Line, TumorHumansHydrogen PeroxideIndocyanine GreenMiceMice, Inbred BALB CMice, NudeNeoplasmsReactive Oxygen SpeciesTumor MicroenvironmentAntineoplastic AgentsCopperHydrogen PeroxideIndocyanine GreenOxygenReactive Oxygen SpeciesOn-demand cascade chemo-drug synthesisROS self-amplificationSonodynamic immunotherapyVehicle-free nanoreactor

Identifiers

PMID41366775
PMCPMC12801933

What OpenQuestion holds

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LicenceCC BY-NC-ND
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.