Evidence map›Paper›PMID 41366682›Full record

ArticleEpidemiology and infection2025

COVID-19 outbreaks in care homes: How does size influence transmission dynamics? A cross-sectional study with implications for outbreak management in small care homes.

Catherine Carey, Éamonn O'Moore, Rita Huyton, Steve Willner, Anand Fernandes, Will Morton, Martyn Regan, Jackie Cassell

Abstract read
In one paragraph

Article in Epidemiology and infection, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Catherine Careyhttps://ror.org/00vbvha87UK Health Security Agency, UK.ORCID 0009-0001-5574-6788
Éamonn O'Moorehttps://ror.org/00vbvha87UK Health Security Agency, UK.
Rita Huytonhttps://ror.org/00vbvha87UK Health Security Agency, UK.
Steve Willnerhttps://ror.org/00vbvha87UK Health Security Agency, UK.
Anand Fernandeshttps://ror.org/00vbvha87UK Health Security Agency, UK.
Will Mortonhttps://ror.org/00vbvha87UK Health Security Agency, UK.ORCID 0000-0002-9595-3212
Martyn Reganhttps://ror.org/00vbvha87UK Health Security Agency, UK.
Jackie Cassellhttps://ror.org/00vbvha87UK Health Security Agency, UK.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

This cross-sectional study investigated how care home size influences COVID-19 transmission dynamics, focusing on outbreaks in England during the second wave of COVID-19 (Wave 2; December 2020 to March 2021) and the Omicron wave (December 2021 to February 2022). Using data from the UK Health Security Agency and the Care Quality Commission, positive SARS-CoV-2 test results were matched to care home registration and occupancy data, examining outbreak trajectories in homes of varying sizes and resident age groups. The study included over 90,000 positive cases across the two waves. Small care homes (SCHs, with 10 or fewer beds), predominantly housing younger adults, showed significantly higher early positivity rates: 42% of residents were positive at outbreak detection, rising to 61% by day 7. In contrast, larger homes had early positivity rates of only 3-6%. These findings suggest that SCHs, often designed for communal living, facilitate rapid within-home transmission similar to household settings. The study concludes that outbreak control strategies in SCHs should differ from those in larger care homes, emphasizing proportionate, individualized approaches that consider resident vulnerability and minimize disruption to social support systems. These results have broader implications for managing future infectious disease outbreaks and support the development of tailored guidance based on care home size and resident demographics.

Indexed as

COVID-19Disease OutbreaksHealth Facility SizeNursing HomesAdolescentAdultAgedAged, 80 and overChildChild, PreschoolCross-Sectional StudiesEnglandFemaleHumansMaleMiddle AgedAttack rateCare homesCOVID-19Infection preventionOutbreak trajectoriesPublic health policySmall care homes (SCHs)Transmission dynamics

Identifiers

PMID41366682
PMCPMC12813716

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.