ArticleBMC neurology2025
Effects of intraoperative hypercapnia on postoperative brain functional network connectivity and cognitive function in adult patients undergoing Clipping Intracranial Aneurysm.
Article in BMC neurology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
backgroundCerebral vasospasm and delayed cerebral ischemia were significant complications in patients undergoing Clipping Intracranial Aneurysm surgery. The impact of intraoperative hypercapnia on postoperative brain function and cognitive outcomes in this patient population was an area of increasing interest. This study aimed to investigate the effects of intraoperative hypercapnia on postoperative brain functional network connectivity and cognitive function in adult patients undergoing Clipping Intracranial Aneurysm.
methodsAdult patients who underwent Clipping Intracranial Aneurysm surgery were included in this retrospective cohort study and were divided into the No Hypercapnia group (PaCO
resultsBaseline characteristics revealed no significant differences between the two groups. Anesthetic doses did not differ significantly between the groups. Postoperative brain functional network connectivity showed significant differences between the groups, with lower connectivity in the Hypercapnia group. Postoperative Mini-Mental State Examination scores were significantly higher in the Hypercapnia group.
conclusionThe study provides novel insights into the effects of intraoperative hypercapnia on postoperative brain functional network connectivity and cognitive function in adult patients undergoing Clipping Intracranial Aneurysm surgery.
trial registrationNot applicable.
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