Evidence map›Paper›PMID 41366641›Full record

ArticleBMC plant biology2025

Transcriptome analysis reveals the role of GA in fruit development of 'Cuiguan' pear (Pyrus pyrifolia).

Wenjing Zhai, Xiangzhan Zhang, Yanan Wang, Suke Wang, Yanli Su, Long Wang, Huabai Xue

Abstract read
In one paragraph

Article in BMC plant biology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Metabolic Engineering for Gibberellic Acid Production inMolecules (Basel, Switzerland) · 2026
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Wenjing Zhai *National Key Laboratory for Germplasm Innovation & Utilization of Horticultural Crops, Zhengzhou Fruit Research Institute, Chinese Academy of Agriculture Sciences, Zhengzhou, Henan, 453004, China.
Xiangzhan Zhang *National Key Laboratory for Germplasm Innovation & Utilization of Horticultural Crops, Zhengzhou Fruit Research Institute, Chinese Academy of Agriculture Sciences, Zhengzhou, Henan, 453004, China.
Yanan WangNational Key Laboratory for Germplasm Innovation & Utilization of Horticultural Crops, Zhengzhou Fruit Research Institute, Chinese Academy of Agriculture Sciences, Zhengzhou, Henan, 453004, China.
Suke WangNational Key Laboratory for Germplasm Innovation & Utilization of Horticultural Crops, Zhengzhou Fruit Research Institute, Chinese Academy of Agriculture Sciences, Zhengzhou, Henan, 453004, China.
Yanli SuNational Key Laboratory for Germplasm Innovation & Utilization of Horticultural Crops, Zhengzhou Fruit Research Institute, Chinese Academy of Agriculture Sciences, Zhengzhou, Henan, 453004, China.
Long WangNational Key Laboratory for Germplasm Innovation & Utilization of Horticultural Crops, Zhengzhou Fruit Research Institute, Chinese Academy of Agriculture Sciences, Zhengzhou, Henan, 453004, China. wanglong02@caas.cn.
Huabai XueNational Key Laboratory for Germplasm Innovation & Utilization of Horticultural Crops, Zhengzhou Fruit Research Institute, Chinese Academy of Agriculture Sciences, Zhengzhou, Henan, 453004, China. xuehuabai@caas.cn.

Funding

Agricultural Science and Technology Innovation Program of Chinese Academy of Agricultural Sciences CAAS-ASTIPEarmarked Fund for China Agriculture Research System CARS-28Henan Province Science and Technology Research Project 232102110180International Science and Technology Cooperation Project of Henan Province 242102521063Key Research and Development Project of Henan Province 241111113500Major Science and Technology Project of Yunnan Province 202302AE090005Major Science and Technology Projects of Henan Province 221100110400Major Science and Technology Projects of Xinjiang Uygur Autonomous Region 2024A02006-1National Key Research and Development Program of China 2021YFD1200202National Key Research and Development Program of China 2023YFD1600803National Natural Science Foundation of China 32202439
6 · The paper itself

Abstract

backgroundFruit size is a crucial agronomic trait that significantly influences fruit quality and economic value. Gibberellin serves as an effective phytohormone that promotes fruit expansion and is widely utilized during the early stages of fruit development. However, the mechanisms underlying GA-mediated fruit enlargement in pear, along with the associated genes and regulatory mechanisms, remain poorly understood.

resultsIn this study, pear cultivar 'Cuiguan' was treated with various combinations of GAs, specifically GA3, GA4 + 7, and GA3 + 4 + 7 at 30 days after flowering. The combination of GA3 + 4 + 7 produced the most pronounced increase in pear fruit size, primarily through promoting elongation. Anatomical analysis revealed that this treatment enhanced both cell proliferation and expansion. RNA-seq was conducted and identified differentially expressed genes associated with GA3 + 4 + 7-mediated fruit enlargement. Functional annotation and enrichment analyses highlighted the involvement of genes related to plant hormone signaling, cell growth, cell division, cell cycle, and transcription factors. Nine DEGs associated with fruit size were validated by RT-qPCR analysis, confirming the RNA-seq results.

conclusionsThis study elucidates the molecular mechanisms by which gibberellins regulate pear fruit development and identify key genes involved in this process, providing a foundation for future research on GA3 + 4 + 7-mediated fruit size regulation.

Indexed as

FruitGibberellinsPlant Growth RegulatorsPyrusTranscriptomeGene Expression ProfilingGene Expression Regulation, PlantGibberellinsPlant Growth RegulatorsFruit developmentGibberellinPearTranscriptome

Identifiers

PMID41366641
PMCPMC12801501

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.