Evidence map›Paper›PMID 41366565›Full record

ArticleNPP - digital psychiatry and neuroscience2025

Viewing social isolation as a complex dynamical system: A theoretical and computational framework.

Samuel J Abplanalp, Joseph S Maimone, Michael F Green

Abstract read
In one paragraph

Article in NPP - digital psychiatry and neuroscience, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Samuel J AbplanalpDesert Pacific Mental Illness Research, Education and Clinical Center, Veterans Affairs Greater Los Angeles Healthcare System, Los Angeles, CA, USA. sabplanalp@mednet.ucla.edu.ORCID http://orcid.org/0000-0003-2894-5607
Joseph S MaimoneDepartment of Psychological and Brain Sciences, Boston University, Boston, MA, USA.
Michael F GreenDesert Pacific Mental Illness Research, Education and Clinical Center, Veterans Affairs Greater Los Angeles Healthcare System, Los Angeles, CA, USA.

Funding

CSRD VA IK2 CX002729U.S. Department of Veterans Affairs (Department of Veterans Affairs) IK2CX002729-01A1
6 · The paper itself

Abstract

Social isolation is a major public health concern linked to increased risk for both psychiatric and physical health conditions. Yet despite the potential consequences of social isolation, our understanding of its nature and how it emerges and evolves over time remains limited. We propose that social isolation should be understood and analyzed as a complex dynamical system. First, we introduce core principles of dynamical systems theory and describe how they can be applied to better understand social isolation. Second, we formalize a dynamical systems model using differential equations. Third, we present simulations based on the differential equations showing how changes in system dynamics may increase or decrease the likelihood of individuals entering a state of social isolation. Fourth, we provide a brief simulation-recovery analysis demonstrating model parameter identifiability from intensive longitudinal data designs. Finally, we offer a simulated example of how intensive longitudinal data could be used to identify signs of transitions between healthy and isolated states. Overall, this framework, both theoretical and computational, helps elucidate the dynamic nature of social isolation and may ultimately inform empirical research and personalized interventions capable of identifying those at risk for transitioning into a state of isolation.

Identifiers

PMID41366565
PMCPMC12689641

What OpenQuestion holds

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.