Evidence map›Paper›PMID 41366527›Full record

SynthesisNeurosurgical review2025

Treatment outcomes of Spetzler-Ponce grade A brain AVMs in a low-volume center: a systematic review and single institution experience.

Patrik Järvelin, Henri Pekonen, Timo Koivisto, Juhana Frösen

Abstract readSystematic Review
In one paragraph

Synthesis in Neurosurgical review, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Patrik JärvelinHemorrhagic Brain Pathology Research Group, Kuopio University Hospital, Kuopio, Finland.
Henri PekonenHemorrhagic Brain Pathology Research Group, Kuopio University Hospital, Kuopio, Finland.
Timo KoivistoDept of Neurosurgery, Kuopio University Hospital, Kuopio, Finland.
Juhana FrösenHemorrhagic Brain Pathology Research Group, Kuopio University Hospital, Kuopio, Finland. Juhana.frosen@tuni.fi.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Arteriovenous malformations of the brain (bAVMs) are complex lesions in the treatment of which patient volumes and subsequent experience are likely to reflect on the outcome. We investigated whether a small neurosurgical center with a limited caseload can achieve similar results to larger centers in treatment of low grade bAVMs. We performed a systematic literature review of studies that have reported outcomes for Spetzler-Ponce A bAVM patients and completed a statistical analysis with a binary random-effects model (Simonian Laird). Since the definition of morbidity varied significantly between studies, we also grouped surgical and endovascular studies according to the definition. We examined treatment outcomes at our own institution and compared them to the literature. In the random effects model based on the literature review, surgery achieved a cure more consistently (98.2%, CI 97.3-99.2%, I

Indexed as

Intracranial Arteriovenous MalformationsNeurosurgical ProceduresEmbolization, TherapeuticEndovascular ProceduresHumansRadiosurgeryTreatment Outcome

Identifiers

PMID41366527
PMCPMC12689658

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.