Evidence map›Paper›PMID 41366519›Full record

ArticleNature cell biology2026

Endoplasmic reticulum disruption stimulates nuclear membrane mechanotransduction.

Zhouyang Shen, Zaza Gelashvili, Philipp Niethammer

Abstract read
In one paragraph

Article in Nature cell biology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed.

  1. Review
  2. Article
  3. Article
  4. Review
  5. Article
  6. Review
  7. Review
  8. Article
  9. Stress transmission towards the nucleus of the cell.Frontiers in cell and developmental biology · 2026
    Review
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

3 authors.

Zhouyang Shen *Cell Biology Program, Memorial Sloan Kettering Cancer Center, New York, NY, USA.ORCID http://orcid.org/0000-0002-6524-8993
Zaza Gelashvili *Cell Biology Program, Memorial Sloan Kettering Cancer Center, New York, NY, USA.ORCID http://orcid.org/0000-0002-2420-3916
Philipp NiethammerCell Biology Program, Memorial Sloan Kettering Cancer Center, New York, NY, USA. niethamp@mskcc.org.ORCID http://orcid.org/0000-0003-4175-4012

Funding

X-RAY CRYSTALLOGRAPHYP30CA008748 · NCI · SLOAN-KETTERING INSTITUTE FOR CANCER RES · PI SELWYN M VICKERS · 1985 to 2026
$347.4M
Chemical and Physical Mechanisms of Wound DetectionR35GM140883 · NIGMS · SLOAN-KETTERING INST CAN RESEARCH · PI Philipp Michael Niethammer · 2021 to 2026
$3.8M
NCI NIH HHS P30 CA008748NIGMS NIH HHS R35 GM140883U.S. Department of Health & Human Services | NIH | National Institute of General Medical Sciences (NIGMS) R35GM140883U.S. Department of Health & Human Services | NIH | NCI | Division of Cancer Epidemiology and Genetics, National Cancer Institute (National Cancer Institute Division of Cancer Epidemiology and Genetics) P30CA008748
6 · The paper itself

Abstract

Cytosolic phospholipase A2 (cPLA

Indexed as

Endoplasmic ReticulumMechanotransduction, CellularNuclear EnvelopeAnimalsCalciumHumansZebrafishCalcium

Identifiers

PMID41366519
PMCPMC12807876

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.