Evidence map›Paper›PMID 41366504›Full record

SynthesisJournal of health, population, and nutrition2025

Effectiveness of technology-based exercise on motor function and quality of life in individuals with multiple sclerosis: an umbrella review.

Mahboubeh Ghayour Najafabadi, Ardalan Shariat, Mahdi Hadi, Kian Bagheri, Hanieh Akbarimehr, Laila Rahmah, Farimah Mahinpour, Nikki Maleki

Abstract readSystematic Review
In one paragraph

Synthesis in Journal of health, population, and nutrition, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Mahboubeh Ghayour NajafabadiDepartment of Behavior and Cognitive Sciences in Sports, Faculty of Sport Sciences and Health, University of Tehran, Tehran, Iran.
Ardalan ShariatDepartment of Digital Health, School of Medicine, Tehran University of Medical Sciences, Tehran, Iran. a-shariat@tums.ac.ir.
Mahdi HadiCenter for Water Quality Research (CWQR), Institute for Environmental Research (IER), Tehran University of Medical Sciences, Tehran, Iran.
Kian BagheriDepartment of Physical Medicine and Rehabilitation, Honor Health, Scottsdale, AZ, USA.
Hanieh AkbarimehrDepartment of Behavior and Cognitive Sciences in Sports, Faculty of Sport Sciences and Health, University of Tehran, Tehran, Iran.
Laila RahmahDepartment of Digital Health, School of Medicine, Tehran University of Medical Sciences, Tehran, Iran.
Farimah MahinpourDepartment of Behavior and Cognitive Sciences in Sports, Faculty of Sport Sciences and Health, University of Tehran, Tehran, Iran.
Nikki MalekiDepartment of Behavior and Cognitive Sciences in Sports, Faculty of Sport Sciences and Health, University of Tehran, Tehran, Iran.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

This umbrella review evaluated the effects of Technology-Based Exercise (Tele-exercise) on balance and Quality of Life (QoL) in individuals with multiple sclerosis (MS). A comprehensive search across multiple databases identified meta-analyses and individual studies published up to June 3, 2025. Eligible studies included meta-analyses assessing tele-exercise interventions, while reviews with insufficient data were excluded. Methodological quality was assessed using the Measurement Tool to Assess Systematic Reviews 2 (AMSTAR-2) checklist. The pooled findings indicate that tele-exercise is not associated with meaningful improvements in balance among individuals with multiple sclerosis (SMD = 0.587, 95% CI: -0.533-1.706, N = 243 based on SMD). Likewise, tele-exercise shows minimal impact on quality of life (QOL) (SMD = 0.169, 95% CI: -0.025-0.362, N = 407 based on SMD). Although trends toward benefit were observed, findings remain inconclusive due to variability in protocols, methodological limitations, and low patient engagement. Overall, tele-exercise is feasible and may support patient-centered care, but current evidence does not confirm significant improvements in balance and QoL for people with MS. Standardized protocols, greater personalization, and higher-quality trials are needed to strengthen future clinical guidelines.

Indexed as

ExerciseExercise TherapyMultiple SclerosisQuality of LifeHumansPostural BalanceTelemedicineDigital healthMeta-analysisMultiple sclerosisTelehealthTelemedicineTele-rehabilitationUmbrella review

Identifiers

PMID41366504
PMCPMC12802298

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.