Evidence map›Paper›PMID 41366408›Full record

Observational studyWorld journal of emergency surgery : WJES2025

How are duodenal trauma managed? A French nationwide study.

Sébastien Frey, Imad Bentellis, Sébastien Gaujoux, Edouard Girard, Julio Abba, Mircea Chirica, Martin Bertrand, Etienne Boutry, Diane Mège, Mathilde Aubert and 35 more

Registry-linked trialAbstract readObservational Study
In one paragraph

Observational study in World journal of emergency surgery : WJES, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06058975 (National Retrospective Study of Duodenal Trauma), which is not on this map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT06058975 completednot on this map

National Retrospective Study of Duodenal Trauma

TypeobservationalSponsorCentre Hospitalier Universitaire de NiceRan2023 to 2024Enrolled135ConditionsDuodenal Diverticulization, Pyloric Exclusion, Gastrojejunostomy, Retrograde DuodenostomyArmsObservational
3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

45 authors.

Sébastien FreyUniversity Côte d'Azur, Nice, France. freysebastien6@gmail.com.ORCID http://orcid.org/0000-0001-5585-7245
Imad BentellisDepartment of Urology, Clinique Saint-Jean, Cagnes-Sur-Mer, France.
Sébastien GaujouxDepartment of Digestive Surgery, Hepato-Bilio-Pancreatic Surgery and Liver Transplantation, Pitié-Salpêtrière Hospital, Assistance Publique - Hôpitaux de Paris, Paris, France.
Edouard GirardCNRS, UMR 5525, VetAgro Sup, Grenoble INP, University Grenoble Alpes, Grenoble, France.
Julio AbbaDepartment of Digestive and Emergency Surgery, University Hospital of Grenoble Alpes, TIMC, Grenoble, France.
Mircea ChiricaDepartment of Digestive and Emergency Surgery, University Hospital of Grenoble Alpes, TIMC, Grenoble, France.
Martin BertrandDepartment of Digestive and Oncological Surgery, University Hospital of Nîmes, Nîmes, France.
Etienne BoutryDepartment of Digestive and Oncological Surgery, University Hospital of Nîmes, Nîmes, France.
Diane MègeDepartment of Digestive and Oncological Surgery, Timone Hospital, University Hospital of Marseille, Marseille, France.
Mathilde AubertDepartment of Digestive and Oncological Surgery, Timone Hospital, University Hospital of Marseille, Marseille, France.
Arnaud AlvesDepartment of Digestive Surgery, University of Caen Normandie, Caen, France.
Emmanuel HornezDepartment of Visceral and Digestive Surgery, Percy Military Teaching Hospital, Clamart, France.
Andrea MulliriDepartment of Digestive Surgery, University of Caen Normandie, Caen, France.
Raffaele BrustiaUPEC - INSERM U955, Team "Pathophysiology and Therapy of Chronic Viral Hepatitis and Related Cancers", University Paris Est-Créteil, Assistance Publique-Hôpitaux de Paris, Paris, France.ORCID http://orcid.org/0000-0001-6426-9533
Hassen HentatiDepartment of Digestive and Hepato-Pancreatic-Biliary Surgery, Assistance Publique-Hôpitaux de Paris, Hôpital Henri-Mondor, Créteil, France.
Lelde LaukaDepartment of Digestive and Hepato-Pancreatic-Biliary Surgery, Assistance Publique-Hôpitaux de Paris, Hôpital Henri-Mondor, Créteil, France.
Alexis LaurentDepartment of Digestive and Hepato-Pancreatic-Biliary Surgery, Assistance Publique-Hôpitaux de Paris, Hôpital Henri-Mondor, Créteil, France.
Daniele SommacaleDepartment of Digestive and Hepato-Pancreatic-Biliary Surgery, Assistance Publique-Hôpitaux de Paris, Hôpital Henri-Mondor, Créteil, France.
Célia TurcoDepartment of Digestive and Oncologic Surgery - Liver Transplantation Unit, University Hospital of Besançon, Besançon, France.
Maude DezeustreDepartment of Digestive and Oncologic Surgery - Liver Transplantation Unit, University Hospital of Besançon, Besançon, France.
Melinda BajulDepartment of Digestive Surgery, Hepato-Bilio-Pancreatic Surgery and Liver Transplantation, Pitié-Salpêtrière Hospital, Assistance Publique - Hôpitaux de Paris, Paris, France.
Antoine CastelDepartment of Hepatobiliary and Digestive Surgery, University Hospital of Rennes, Rennes, France.
Olivier FacyDepartment of Digestive and Oncological Surgery, University Hospital of Dijon, Dijon, France.
Robin GrelletDepartment of Digestive and Oncological Surgery, University Hospital of Dijon, Dijon, France.
Laurent SulpiceDepartment of Hepatobiliary and Digestive Surgery, University Hospital of Rennes, Rennes, France.
Fabrice MénégauxDepartment of Digestive Surgery, Hepato-Bilio-Pancreatic Surgery and Liver Transplantation, Pitié-Salpêtrière Hospital, Assistance Publique - Hôpitaux de Paris, Paris, France.
Maxime DelestreDepartment of Digestive and Visceral Surgery, University Hospital of Angers, Angers, France.
Emilie LermiteDepartment of Digestive and Visceral Surgery, University Hospital of Angers, Angers, France.
Tristan MonchalDepartment of Visceral, Digestive, and Oncological Surgery, Sainte-Anne Military Teaching Hospital, Toulon, France.
Rida AmrouDepartment of Digestive and Hepato-Pancreatic-Biliary Surgery, Assistance Publique-Hôpitaux de Paris, Hôpital Henri-Mondor, Créteil, France.
Ophélie Bacoeur-OuzillouDepartment of Digetive and Hepatobiliary Surgery, Estaing Hospital, University Hospital of Clermont-Ferrand, Clermont-Ferrand, France.
Denis PezetDepartment of Digetive and Hepatobiliary Surgery, Estaing Hospital, University Hospital of Clermont-Ferrand, Clermont-Ferrand, France.
Jeremy BonnetDepartment of Digestive Surgery, University Hospital of Guadeloupe, Pointe-À-Pitre, France.
Emmanuel BucDepartment of Digetive and Hepatobiliary Surgery, Estaing Hospital, University Hospital of Clermont-Ferrand, Clermont-Ferrand, France.
Guillaume PassotDepartment of Digestive and Oncological Surgery, University Hospital of Lyon Sud, Lyon, France.
Anne-Sophie SchneckDepartment of Digestive Surgery, University Hospital of Guadeloupe, Pointe-À-Pitre, France.
David Jérémie BirnbaumDepartment of Visceral and Digestive Surgery, Hôpital Nord, University Hospital of Marseille, Marseille, France.
Pierre-Yves BlancDepartment of Digestive Surgery, University Hospital of Saint-Etienne, Saint-Etienne, France.
Bertrand Le RoyDepartment of Digestive Surgery, University Hospital of Saint-Etienne, Saint-Etienne, France.
Olivier MonneuseEmergency Surgical Departement, Trauma Center, Edouard Herriot Hospital, Université Claude Bernard Lyon 1, Lyon, France.
Quentin RodriguezDepartment of Digestive Surgery and Organ Transplantation, University Hospital of Toulouse, Toulouse, France.
Bertrand SucDepartment of Digestive Surgery and Organ Transplantation, University Hospital of Toulouse, Toulouse, France.
Patrick BaquéUniversity Côte d'Azur, Nice, France.
Vincent DubuissonDepartment of Digestive Surgery, Pellegrin Hospital, University Hospital of Bordeaux, Bordeaux, France.
Damien MassalouUniversity Côte d'Azur, Nice, France.ORCID http://orcid.org/0000-0002-2015-1661

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundDuodenal injuries are rare, associated with a significant morbidity. Their management is challanging and remains controversial.

methodsA retrospective study of all consecutive patients with duodenal trauma managed in 21 French trauma centers from 2004 to 2023. Clinical data, trauma mechanisms, injury severity, treatment modalities and outcomes were collected. Specific attention was given to surgical techniques such as damage control laparotomy, primary repair only and duodenal diversion. Statistical analysis was performed to identify factors associated with duodenal leak, severe morbidity and mortality.

resultsOne hundred and thirty-five patients (71.7% male, mean age 35 years) were included, 64% with blunt trauma. Duodenal AAST grades I-II occurred in 68.2% and grades III-V in 31.8%. A discrepancy between radiologic evaluation and intraoperative observations was present in 30.8% of cases, underestimating injury severity in 29.1%. Initial management was nonoperative for 12.7%. Damage control laparotomy was required in 36.6%. Operated patients underwent direct suture (69.2%), duodenal resection (24.4%), duodenal diversion (35.8%). Duodenal leaks occurred in 23.7%, significantly increased by hemodynamic instability (OR = 3.08, p = 0.015) and associated pancreatic trauma (OR = 2.44, p = 0.044). Reoperation rate was 18.5%, for missed duodenal injury (16%) and/or for duodenal leak (32%). Mean length of stay was 27 days. Major morbidity was 27.4% and 30-day mortality 10.4%. The injury severity score was the only predictive factor of major morbidity and mortality.

conclusionsDuodenal trauma remains a severe condition managed mostly with primary repair, where duodenal leak-significantly associated with hemodynamic instability and pancreatic injury, is a major driver of reintervention.

trial registrationThis study was registered on Clinical Trials under the registration numbe NCT06058975.

Indexed as

Abdominal InjuriesDuodenumAdolescentAdultFemaleFranceHumansInjury Severity ScoreMaleMiddle AgedRetrospective StudiesTrauma CentersAbdominal traumaDamage control laparotomyDuodenal diversionDuodenal injuryDuodenal leakDuodenal suture

Identifiers

PMID41366408
PMCPMC12690877

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.