ReviewBMC pulmonary medicine2025
A case of pulmonary nodular lesion caused by Tropheryma whipplei infection: a case report and literature review.
Review in BMC pulmonary medicine, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
1 citing paper in PubMed.
- Pulmonary infection caused byTranslational pediatrics · 2026Article
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Authors and funding
3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundTropheryma whipplei is a Gram-positive aerobic bacillus belonging to the phylum Actinobacteria. It is the causative agent of Whipple's disease, a multi-systemic illness that can lead to pneumonia when the lungs are involved. Currently, there is no expert consensus regarding diagnostic criteria for T. whipplei pneumonia. Its clinical manifestations and imaging features lack specificity, often resulting in misdiagnosis or missed diagnosis. CASE PRESENTATION: A 69-year-old male presented with intermittent right-sided chest pain and coughing with expectoration. Initial chest imaging suggested a high probability of a malignant lung tumor. Following comprehensive examinations and treatments, the tumor diagnosis was excluded, and an infectious lesion was confirmed. Positron Emission Tomography/Computed Tomography (PET/CT) revealed a marked increase in
conclusionsThe symptoms of T. whipplei infection involving the lungs are indeed nonspecific, and pulmonary nodules are perhaps its most common imaging manifestation. The tNGS has improved the efficiency of pathogenic microorganism diagnosis. Where feasible, tNGS testing should be promptly implemented to avoid misdiagnosis or missed diagnosis. PET/CT can be used as a potential auxiliary diagnostic tool for pulmonary nodules associated with T. whipplei infection.
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