Evidence map›Paper›PMID 41366316›Full record

Trial reportBMC geriatrics2025

Integrated primary care for home-dwelling older adults with mild cognitive impairment in China: a hybrid effectiveness-implementation trial protocol.

Shasha Yuan, Jiaqi Chen, Zheng Wang, Haifeng Zhang

Abstract readRandomized Controlled Trial
In one paragraph

Trial report in BMC geriatrics, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Shasha YuanInstitute of Medical Information/Medical Library, Chinese Academy of Medical Sciences & Peking Union Medical College, No. 3 Yabao Road, Chaoyang District, Beijing, 100020, China. yuanshasha417@163.com.
Jiaqi ChenInstitute of Medical Information/Medical Library, Chinese Academy of Medical Sciences & Peking Union Medical College, No. 3 Yabao Road, Chaoyang District, Beijing, 100020, China.
Zheng WangInstitute of Medical Information/Medical Library, Chinese Academy of Medical Sciences & Peking Union Medical College, No. 3 Yabao Road, Chaoyang District, Beijing, 100020, China.
Haifeng ZhangPeking University Sixth Hospital, Peking University Institute of Mental Health, NHC Key Laboratory of Mental Health (Peking University), National Clinical Research Center for Mental Disorders (Peking University Sixth Hospital), Beijing, 100191, China.

Funding

Capital's Funds for Health Improvement and Research CFH2024-2G-4311Ministry of Education (MOE) Humanities and Social Sciences Grant 22YJC630196National Natural Science Foundation of China 72304282
6 · The paper itself

Abstract

backgroundWith China’s rapidly aging population, addressing the health management of mild cognitive impairment (MCI) in community settings has become crucial for dementia prevention. This study focuses on developing an integrated primary care intervention (IPC) within primary care system to support home-dwelling older adults with MCI and explore the underlying barriers based on the Consolidated Framework for Implementation Research (CFIR) to the implementation and further scale up of the IPC intervention.

methodsThis study employs a hybrid effectiveness-implementation research type II design. The randomized controlled trail will be conducted to evaluate the IPC intervention for older adults with MCI through primary care networks. The intervention group receiving 16-week family doctor contract services (including online cognitive training, enhanced health management, and usual care) and the control group receiving usual care only. Effectiveness will be measured through changes in participants’ cognitive function (primary outcome), self-efficacy and quality of life (secondary outcome), complemented by cost-effectiveness analysis. Implementation factors will be examined through the CFIR before and during the intervention process. DISCUSSION: This study is expected to demonstrate the effectiveness and implementation of the IPC intervention in managing older MCI adults within primary care setting. The implementation analysis will identify key factors for scaling up the intervention within China’s primary care system, including necessary policy adjustments and training requirements for primary care providers. The findings will provide both practical guidance for China’s dementia prevention strategies and contribute to global knowledge about implementing community-based cognitive health interventions in primary care settings.

trial registrationChinese Clinical Trial Registry ChiCTR2500099744. Registered 27 March 2025.

Indexed as

Cognitive DysfunctionDelivery of Health Care, IntegratedPrimary Health CareAgedAging in PlaceChinaCognitive TrainingCost-Benefit AnalysisFemaleHumansMaleEffectiveness-implementation hybrid trialFamily doctor contract servicesImplementation scienceIntegrated primary careMild cognitive impairment

Identifiers

PMID41366316
PMCPMC12687523

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.