Evidence map›Paper›PMID 41366315›Full record

Trial reportBMC pediatrics2025

Mobile app improves treatment of functional constipation in children: a randomized single-blind study.

Julia Leszkowicz, Wojciech Nazar, Karolina Wysokińska-Zakrzewska, Agata Zdun-Ryżewska, Paulina Czadek-Asner, Magdalena Dettlaff-Dunowska, Katarzyna Plata-Nazar, Agnieszka Szlagatys-Sidorkiewicz

Registry-linked trialAbstract readRandomized Controlled Trial
In one paragraph

Trial report in BMC pediatrics, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT07025135 (Evaluation of the Effectiveness of a Mobile Application in the Treatment of Children With Functional Constipation), which is not on this map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT07025135 nacompletednot on this map

Evaluation of the Effectiveness of a Mobile Application in the Treatment of Children With Functional Constipation

TypeinterventionalSponsorMedical University of GdanskRan2023 to 2024Enrolled100ConditionsConstipation - FunctionalArmscomparison between use of mobile app, Patient-caregiver dyad using printed recommendations
3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Julia LeszkowiczDepartment of Paediatrics, Gastroenterology, Allergology & Paediatric Nutrition, Medical University of Gdańsk, Gdańsk, Poland. julia.leszkowicz@gumed.edu.pl.
Wojciech NazarLaboratory of Experimental and Translational Allergology, Division of Allergology Department of Pulmonology & Allergology, Medical University of Gdańsk, Gdańsk, Poland.
Karolina Wysokińska-ZakrzewskaDivision of Quality of Life Research, Department of Psychology, faculty of Health Sciences, Medical University of Gdansk, Gdańsk, Poland.
Agata Zdun-RyżewskaDivision of Quality of Life Research, Department of Psychology, faculty of Health Sciences, Medical University of Gdansk, Gdańsk, Poland.
Paulina Czadek-AsnerDepartment of Paediatrics, Gastroenterology, Allergology & Paediatric Nutrition, Medical University of Gdańsk, Gdańsk, Poland.
Magdalena Dettlaff-DunowskaDepartment of Paediatrics, Gastroenterology, Allergology & Paediatric Nutrition, Medical University of Gdańsk, Gdańsk, Poland.
Katarzyna Plata-NazarDepartment of Paediatrics, Gastroenterology, Allergology & Paediatric Nutrition, Medical University of Gdańsk, Gdańsk, Poland.
Agnieszka Szlagatys-SidorkiewiczDepartment of Paediatrics, Gastroenterology, Allergology & Paediatric Nutrition, Medical University of Gdańsk, Gdańsk, Poland.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundFunctional constipation is one of the most prevalent functional gastrointestinal disorders in the pediatric population, frequently resulting in quality of life impairment and elevated healthcare costs. Despite the availability of evidence-based treatment guidelines, adherence remains an essential challenge to achieving sustained therapeutic success.

methodsThis randomized, single-blind per-protocol study assessed the efficacy of a mobile application compared to conventional printed educational materials in supporting the management of functional constipation in children aged 4-12 years. 100 patient-caregiver dyads were randomized into two arms: an intervention group using a mobile application and a control group receiving printed recommendations. Clinical outcomes were evaluated over a six-month follow-up using the Pediatric Quality of Life Inventory™ (PedsQL™) Gastrointestinal Symptoms Module.

resultsThere were 113 complete questionnaires, 65 from adults and 48 from children. Participants in the intervention cohort demonstrated significantly greater improvements in symptom control (mean difference 21.4 vs. 12.3 points; p = 0.014), particularly in the domains of constipation, abdominal pain, and bloating.

conclusionsThe mobile application's interactive features, behavioral tracking tools, and integrated reward system appeared to enhance adherence and self-efficacy among users. Overall, the results support the potential utility of mobile health interventions as adjuncts to standard care in managing pediatric functional constipation.

trial registrationClinicalTrials.gov NCT07025135. Registered 17/06/2025 (trial start 05/02/2023).

trial registrationClinicalTrials.gov NCT07025135. Registered 17/06/2025 (trial start 05/02/2023).

Indexed as

ConstipationMobile ApplicationsAdultChildChild, PreschoolFemaleHumansMalePatient ComplianceQuality of LifeSelf EfficacySingle-Blind MethodTreatment OutcomeAdherenceConstipationFunctional disordersMobile app

Identifiers

PMID41366315
PMCPMC12687499

What OpenQuestion holds

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.