Evidence map›Paper›PMID 41366214›Full record

ArticleNature communications2025

Distinct structural features of Pseudomonas aeruginosa ATP synthase revealed by cryo-electron microscopy.

Meghna Sobti, Adam P Gunn, Simon H J Brown, Lauren Zavan, Vesper M Fraunfelter, Amanda L Wolfe, Christopher A McDevitt, P Ryan Steed, Alastair G Stewart

Abstract read
In one paragraph

Article in Nature communications, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Meghna SobtiMolecular, Structural and Computational Biology Division, The Victor Chang Cardiac Research Institute, Darlinghurst, NSW, Australia.
Adam P GunnDepartment of Microbiology and Immunology, The Peter Doherty Institute for Infection and Immunity, The University of Melbourne, Parkville, VIC, Australia.ORCID http://orcid.org/0000-0002-8181-4975
Simon H J BrownSchool of Science, Molecular Horizons, and the Australian Research Council Centre for Cryo-electron Microscopy of Membrane Proteins, University of Wollongong, Wollongong, NSW, Australia.ORCID http://orcid.org/0000-0003-3997-4614
Lauren ZavanDepartment of Microbiology and Immunology, The Peter Doherty Institute for Infection and Immunity, The University of Melbourne, Parkville, VIC, Australia.
Vesper M FraunfelterDepartment of Chemistry and Biochemistry, University of North Carolina Asheville, Asheville, NC, USA.ORCID http://orcid.org/0009-0009-1454-5443
Amanda L WolfeDepartment of Chemistry and Biochemistry, University of North Carolina Asheville, Asheville, NC, USA.ORCID http://orcid.org/0000-0003-1867-6861
Christopher A McDevittDepartment of Microbiology and Immunology, The Peter Doherty Institute for Infection and Immunity, The University of Melbourne, Parkville, VIC, Australia.ORCID http://orcid.org/0000-0003-1596-4841
P Ryan SteedDepartment of Chemistry and Biochemistry, University of North Carolina Asheville, Asheville, NC, USA.
Alastair G StewartMolecular, Structural and Computational Biology Division, The Victor Chang Cardiac Research Institute, Darlinghurst, NSW, Australia. a.stewart@victorchang.edu.au.ORCID http://orcid.org/0000-0002-2070-6030

Funding

ChimeraX -- Next Generation Visualization and Analysis Software for Multiscale ModelingR01GM129325 · NIGMS · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI FERRIN, THOMAS E · 2018 to 2025
$5.2M
Targeted development and selective delivery of small molecule antibiotics for the treatment of multidrug resistant Pseudomonas aeruginosa infectionsR15AI163474 · NIAID · UNIVERSITY OF NORTH CAROLINA ASHEVILLE · PI Amanda Lynn Wolfe · 2021 to 2026
$889k
Function and dynamics of rotor-stator interactions in the proton-translocating Fo motor of ATP synthaseR15GM134453 · NIGMS · UNIVERSITY OF NORTH CAROLINA ASHEVILLE · PI STEED, PHILLIP RYAN · 2019 to 2019
$327k
Department of Education and Training | Australian Research Council (ARC) DP250101405Department of Education and Training | Australian Research Council (ARC) IC200100052Department of Health | National Health and Medical Research Council (NHMRC) 2016308Department of Health | National Health and Medical Research Council (NHMRC) 2036811NIAID NIH HHS R15 AI163474NIGMS NIH HHS R01 GM129325NIGMS NIH HHS R15 GM134453
6 · The paper itself

Abstract

F

Indexed as

Bacterial ProteinsProton-Translocating ATPasesPseudomonas aeruginosaAdenosine TriphosphateBinding SitesCryoelectron MicroscopyModels, MolecularProtein ConformationProtein SubunitsZincAdenosine TriphosphateBacterial ProteinsProtein SubunitsProton-Translocating ATPasesZinc

Identifiers

PMID41366214
PMCPMC12796488

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.