Evidence map›Paper›PMID 41366108›Full record

ArticleAesthetic plastic surgery2026

A Quantitative Measurement Method to Evaluate the Aesthetic Effect of Injectable Fillers for Correcting Nasolabial Fold Wrinkles.

Huiling Deng, Lishuai Shi, Traidit Thianthanyakij, Guobao Wang, Haiyan Cui

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Article in Aesthetic plastic surgery, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

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Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

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No citing paper in PubMed yet.

4 · The record

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PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Huiling DengDepartment of Plastic and Cosmetic Surgery, Tongji Hospital, School of Medicine, Tongji University, Shanghai, 200092, China.ORCID 0000-0003-3655-2184
Lishuai ShiDepartment of Plastic and Cosmetic Surgery, Tongji Hospital, School of Medicine, Tongji University, Shanghai, 200092, China.
Traidit ThianthanyakijDepartment of Plastic and Cosmetic Surgery, Tongji Hospital, School of Medicine, Tongji University, Shanghai, 200092, China.
Guobao WangDepartment of Plastic and Cosmetic Surgery, Tongji Hospital, School of Medicine, Tongji University, Shanghai, 200092, China. wgbmed@163.com.
Haiyan CuiDepartment of Plastic and Cosmetic Surgery, Tongji Hospital, School of Medicine, Tongji University, Shanghai, 200092, China. u2beauty1@sina.com.

Funding

National Natural Science Foundation of China 82202803
6 · The paper itself

Abstract

backgroundCurrently, there are few methods that can objectively and quantitatively evaluate the aesthetic effect of injectable fillers in correcting nasolabial fold wrinkles (NLFWs). The purpose of this study is to construct a new approach for evaluating the aesthetic effect of injectable fillers in correcting NLFWs, to study the changes in soft tissue measurement indexes both before and after the treatment, and to explore their clinical significance, thereby providing objective data support for the clinical treatment of NLFWs and assessment of its aesthetic effect.

methodsThe aesthetic effect of 32 patients who received poly-L-lactic acid injectable fillers to correct NLFWs was objectively and comprehensively evaluated using the multidirectional "Point-angle combination" measurements constructed in this study.

resultsThere were varying degrees of decrease in the horizontal and vertical ratios of NLFWs compared to the baseline level, and the NLFW endpoints shifted upward and inward to be closer to the nasal wings on both sides, and the length, depth, and symmetry of NLFWs on the left and right faces of the patients were all improved in different degrees.

conclusionThe multidimensional "Point-angle combination" measurements constructed in this study showed excellent feasibility in assessing the aesthetic effect of injectable fillers in correcting NLFWs and can objectively and quantitatively measure the changes in NLFWs severity in patients. LEVEL OF EVIDENCE I: This journal requires that authors assign a level of evidence to each article. For a full description of these Evidence-Based Medicine ratings, please refer to the Table of Contents or the online Instructions to Authors www.springer.com/00266 .

Indexed as

Cosmetic TechniquesDermal FillersNasolabial FoldSkin AgingAdultEstheticsFemaleHumansMaleMiddle AgedPolyestersTreatment OutcomeDermal FillersPolyesterspoly(lactide)Aesthetic effectInjectable fillerMultidimensional “Point-angle combination” measurementsNasolabial fold wrinklesPoly-L-lactic acid

Identifiers

PMID41366108

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.