Evidence map›Paper›PMID 41366091›Full record

ArticleSpinal cord2026

Spinal cord injury research and national institutes of health funding: a call to action.

Jason Silvestre, John C Martin, Warren Roth, Robert J Ferdon, Charles A Reitman, James P Lawrence, Michael G Fehlings, Robert A Ravinsky

Abstract read
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In one paragraph

Article in Spinal cord, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Jason SilvestreMedical University of South Carolina, Charleston, SC, US. jasonsilvestremd@gmail.com.ORCID 0000-0002-5831-0760
John C MartinMedical University of South Carolina, Charleston, SC, US.
Warren RothMedical University of South Carolina, Charleston, SC, US.
Robert J FerdonMedical University of South Carolina, Charleston, SC, US.ORCID 0009-0008-1885-5812
Charles A ReitmanMedical University of South Carolina, Charleston, SC, US.
James P LawrenceMedical University of South Carolina, Charleston, SC, US.
Michael G FehlingsUniversity of Toronto, Toronto, CA, US.ORCID 0000-0002-5722-6364
Robert A RavinskyMedical University of South Carolina, Charleston, SC, US.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

STUDY

designCross-sectional study.

objectivesThe magnitude and nature of National Institutes of Health (NIH) funding for spinal cord injury (SCI) research is poorly characterized. This study elucidates the portfolio of NIH grants awarded for SCI research.

settingN/A

methodsData on NIH grants awarded for SCI research were extracted from the NIH RePORTER database (2013-2023). NIH funding was analyzed for twenty-five clinical areas and compound annual growth rates (CAGRs) were calculated over the study period.

resultsFrom 2013-2023, the NIH extramural research budget increased from $28.3 to $45.0 billion (CAGR 4.7%). A total of $986 million was awarded for SCI research, which increased from $93.6 to $97.7 million over the study period (CAGR 0.4%). Among the twenty-five clinical areas, dementia ($21.8 billion, CAGR 18.7%) and diabetes ($20.6 billion, CAGR 21.5%) had the most NIH funding. For SCI research, most NIH funding was awarded by the National Institute of Neurological Disorders and Stroke (67%) via the R01 (57%) grant mechanism. The clinical areas receiving the most NIH funding for SCI research were disease mechanisms (47%), prosthetics (22%), biologic therapies (18%), and pharmacologic therapies (6%). Several principal investigator characteristics were associated with higher NIH funding totals for SCI research including male (P < 0.001), full professor (P < 0.001), and MD, PhD degree (P = 0.044).

conclusionsGrowth in the annual NIH budget for SCI research has not kept pace with growth in the overall NIH extramural research budget. Future strategies are needed to support PIs in obtaining NIH grant funding for SCI research.

Indexed as

Biomedical ResearchFinancing, GovernmentNational Institutes of Health (U.S.)Research Support as TopicSpinal Cord InjuriesCross-Sectional StudiesFemaleHumansMaleUnited States

Identifiers

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.