Evidence map›Paper›PMID 41366004›Full record

SynthesisScientific reports2025

Meta-analysis of the effects of Internet-based health education methods on post-treatment recovery and quality of life in patients with colorectal cancer.

Hang Zhang, Lei Wang, Yuehua Han, Jun Wang, Xiaoli Jin

Abstract readMeta-Analysis
In one paragraph

Synthesis in Scientific reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Hang ZhangDepartment of Gastroenterology Surgery, The Second Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, 310000, Zhejiang, China.
Lei WangDepartment of Emergency Medicine, The Second Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, 310000, Zhejiang, China.
Yuehua HanDepartment of Gastroenterology, The Second Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, 310000, Zhejiang, China.
Jun WangDepartment of Gastroenterology Surgery, The Second Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, 310000, Zhejiang, China. wangjunoscar@zju.edu.cn.
Xiaoli JinDepartment of Gastroenterology Surgery, The Second Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, 310000, Zhejiang, China. jinxiaoli@zju.edu.cn.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Internet-based health education has been increasingly integrated into perioperative and postoperative management for patients with colorectal cancer (CRC). However, the overall effectiveness of such interventions on psychological well-being and recovery outcomes remains uncertain. A systematic search was conducted in PubMed, Embase, Cochrane Library, Web of Science, CNKI, and Wanfang databases from inception to December 2024. Eligible studies included randomized controlled trials (RCTs) or cohort studies evaluating Internet-based health education interventions in CRC patients, with control groups receiving conventional care or standard education. Primary outcomes were SAS (Self-Rating Anxiety Scale) and SDS (Self-Rating Depression Scale), and 36-Item Short Form Health Survey quality of life (QOL); secondary outcomes included postoperative recovery indicators such as time to first flatus and length of hospital stay. Data were pooled using random-effects meta-analyses, and heterogeneity was assessed using the I² statistic. A total of 20 studies (19 RCTs and 1 cohort study) involving 1540 participants were included. Meta-analysis showed that Internet-based health education methods can significantly improve self-care skills (SMD = 2.62, 95%CI: 0.25 ~ 4.99, P = 0.03), significantly reduce SAS (SMD= -0.97, 95%CI: -1.11~-0.83, P < 0.01) and SDS scores (SMD= -2.08, 95%CI: -3.54~-0.63, P = 0.01), reduce the incidence of postoperative complications (Log(OR)= -1.08, 95%CI: -1.45~-0.72, P < 0.01), and significantly improve QOL scores (SMD = 0.51, 95%CI: 0.29 ~ 0.72, P < 0.01). Considerable heterogeneity was observed in some analyses (I² > 90%). Subgroup analysis showed that the intervention method based on the WeChat platform was more effective in improving SAS (SMD= -1.06, P < 0.01). Internet-based health education, especially interactive and feedback-driven interventions delivered via mobile platforms, could effectively improve recovery outcomes among CRC patients in the perioperative and follow-up phases. Future studies should employ multicenter, long-term RCTs to verify sustainability, optimize intervention components, and assess cost-effectiveness.

Indexed as

Colorectal NeoplasmsHealth EducationInternet-Based InterventionPatient Education as TopicQuality of LifeHumansInternetRandomized Controlled Trials as TopicSelf CareColorectal cancerInternet health educationMeta-analysisPoor translationPostoperative recoveryQuality of life

Identifiers

PMID41366004
PMCPMC12800205

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.