Evidence map›Paper›PMID 41365681›Full record

ArticleACS infectious diseases2026

IL-33/ST2 Signaling Protects the Heart by Restraining Inflammation and Parasite Burden during

Marcelo Eduardo Cardozo, Tatyane Martins Cirilo, Jorge Lucas Nascimento Souza, José Bryan da Rocha Rihs, Isabela de Brito Duval, Fernando Bento Rodrigues Oliveira, Mayra Ricci, Laura Lis de Oliveira Santos, Livia Fernanda Santana, Luiza Pinheiro Silva and 15 more

Abstract read
In one paragraph

Article in ACS infectious diseases, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Review
  2. Article
  3. Article
  4. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

25 authors.

Marcelo Eduardo CardozoLaboratory of Immunobiology and Parasite Control, Institute of Biological Sciences, Universidade Federal de Minas Gerais, Belo Horizonte 31270-901, Brazil.ORCID 0009-0000-4337-625X
Tatyane Martins CiriloLaboratory of Immunobiology and Parasite Control, Institute of Biological Sciences, Universidade Federal de Minas Gerais, Belo Horizonte 31270-901, Brazil.
Jorge Lucas Nascimento SouzaLaboratory of Immunobiology and Parasite Control, Institute of Biological Sciences, Universidade Federal de Minas Gerais, Belo Horizonte 31270-901, Brazil.
José Bryan da Rocha RihsLaboratory of Immunobiology and Parasite Control, Institute of Biological Sciences, Universidade Federal de Minas Gerais, Belo Horizonte 31270-901, Brazil.
Isabela de Brito DuvalLaboratory of Immunobiology and Parasite Control, Institute of Biological Sciences, Universidade Federal de Minas Gerais, Belo Horizonte 31270-901, Brazil.
Fernando Bento Rodrigues OliveiraLaboratory of Immunoregulation of Infectious Diseases, Institute of Biological Sciences, Universidade Federal de Minas Gerais, Belo Horizonte 31270-901, Brazil.
Mayra RicciLaboratory of Immunoregulation of Infectious Diseases, Institute of Biological Sciences, Universidade Federal de Minas Gerais, Belo Horizonte 31270-901, Brazil.ORCID 0000-0003-2074-1204
Laura Lis de Oliveira SantosLaboratory of Immunoregulation of Infectious Diseases, Institute of Biological Sciences, Universidade Federal de Minas Gerais, Belo Horizonte 31270-901, Brazil.
Livia Fernanda SantanaLaboratory of Immunoregulation of Infectious Diseases, Institute of Biological Sciences, Universidade Federal de Minas Gerais, Belo Horizonte 31270-901, Brazil.
Luiza Pinheiro SilvaLaboratory of Immunoregulation of Infectious Diseases, Institute of Biological Sciences, Universidade Federal de Minas Gerais, Belo Horizonte 31270-901, Brazil.
Chiara Cassia Oliveira AmorimLaboratory of Immunobiology and Parasite Control, Institute of Biological Sciences, Universidade Federal de Minas Gerais, Belo Horizonte 31270-901, Brazil.
Ana Rafaela Antunes-PortoLaboratory of Immunobiology and Parasite Control, Institute of Biological Sciences, Universidade Federal de Minas Gerais, Belo Horizonte 31270-901, Brazil.
Izabela da Silva OliveiraLaboratory of Immunobiology and Parasite Control, Institute of Biological Sciences, Universidade Federal de Minas Gerais, Belo Horizonte 31270-901, Brazil.
Ana Laura Grossi de OliveiraLaboratory of Immunobiology and Parasite Control, Institute of Biological Sciences, Universidade Federal de Minas Gerais, Belo Horizonte 31270-901, Brazil.
Luisa Vitor Braga do AmaralLaboratory of Immunobiology and Parasite Control, Institute of Biological Sciences, Universidade Federal de Minas Gerais, Belo Horizonte 31270-901, Brazil.
Gabriela Gomes Monteiro LemosLaboratory of Immunobiology and Parasite Control, Institute of Biological Sciences, Universidade Federal de Minas Gerais, Belo Horizonte 31270-901, Brazil.
Getúlio Mota E Silva JuniorLaboratory of Immunobiology and Parasite Control, Institute of Biological Sciences, Universidade Federal de Minas Gerais, Belo Horizonte 31270-901, Brazil.
Ivan Lobo de Sousa MarquesLaboratory of Cellular Electrophysiology, Institute of Biological Sciences, Universidade Federal de Minas Gerais, Belo Horizonte 31270-901, Brazil.
Marina Possa Dos ReysLaboratory of Comparative Pathology, Institute of Biological Sciences, Universidade Federal de Minas Gerais, Belo Horizonte 31270-901, Brazil.
Geovanni Dantas CassaliLaboratory of Comparative Pathology, Institute of Biological Sciences, Universidade Federal de Minas Gerais, Belo Horizonte 31270-901, Brazil.
Artur Santos-MirandaLaboratory of Cellular Electrophysiology, Institute of Biological Sciences, Universidade Federal de Minas Gerais, Belo Horizonte 31270-901, Brazil.
Luisa Mourão Dias MagalhãesLaboratory of Interactions in ImmunoParasitology, Institute of Biological Sciences, Universidade Federal de Minas Gerais, Belo Horizonte 31270-901, Brazil.
Lilian Lacerda BuenoLaboratory of Immunobiology and Parasite Control, Institute of Biological Sciences, Universidade Federal de Minas Gerais, Belo Horizonte 31270-901, Brazil.ORCID 0000-0003-3510-4590
Fabiana Simão MachadoPost-graduation Program in Health Sciences: Infectious Diseases and Tropical Medicine, Faculdade de Medicina, Universidade Federal de Minas Gerais, Belo Horizonte 30130-100, Brazil.
Ricardo Toshio FujiwaraLaboratory of Immunobiology and Parasite Control, Institute of Biological Sciences, Universidade Federal de Minas Gerais, Belo Horizonte 31270-901, Brazil.ORCID 0000-0002-4713-575X

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Chagas disease (CD), caused by the parasite

Indexed as

Chagas DiseaseInterleukin-1 Receptor-Like 1 ProteinInterleukin-33Trypanosoma cruziAnimalsChagas CardiomyopathyDisease Models, AnimalFemaleHeartInflammationMiceMice, Inbred C57BLMice, KnockoutMyocarditisMyocardiumParasite LoadIl1rl1 protein, mouseIl33 protein, mouseInterleukin-1 Receptor-Like 1 ProteinInterleukin-33Chagas diseasecytokinesinflammationleukocytesmyocarditis

Identifiers

PMID41365681
PMCPMC12797244

What OpenQuestion holds

Textmetadata
LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.