ArticleSurgical innovation2026
Comparing the Effects of Absorbable Polyglycolic Acid-Coated Tube and Polypropylene Suture Repairs on Stricture Formation in Biliary Anastomosis.
Article in Surgical innovation, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
9 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
BackgroundOur study aimed to compare the effects of repair using polypropylene suture material vs polyglycolic acid-coated (PGA) tube on the development of biliary strictures in rat common bile duct incisions.MethodsThirty female rats were randomly divided into three groups. A controlled defect was created in the common bile duct. In Group 1, the defect was repaired with 8/0 polyglycolic acid; in Group 2, with 8/0 polypropylene; and in Group 3, with 8/0 polyglycolide-co-lactide followed by wrapping with an absorbable polyglycolic acid mesh tube. In the second surgical step, at 3 months postoperatively, blood samples were again taken from all subjects, liver biopsies were obtained, and the repaired bile duct area was resected for histopathological evaluation. Liver biopsies obtained before bile duct repair and at 3 months after repair were compared among the groups. Anastomotic sites and proximal bile duct diameters were compared between groups at 3 months post-repair.ResultsPostoperative ALT and GGT levels were significantly higher in Group 1 rats, while ALP levels were statistically significantly lower in Group 2 rats. Epithelial hyperplasia was detected in 20% of rats in Group 3, with fewer proliferative fibroblasts and less collagen scar tissue compared with those in other groups. The Portal edema rate was significantly lower in Group 3 than in Groups 1 and 2.ConclusionsThe use of PGA -coated tubes after PGLA suturing suggests that these tubes may reduce strictures in biliary repair in rats by maintaining a wider anastomotic diameter.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.