Evidence map›Paper›PMID 41364759›Full record

ArticleProceedings of the National Academy of Sciences of the United States of America2025

Organization principles of dynamic three-dimensional genome architecture associated with centromere clustering states.

Satya Dev Polisetty, Shuvadip Dutta, Rakesh Netha Vadnala, Dimple Notani, Ranjith Padinhateeri, Kaustuv Sanyal

Abstract read
In one paragraph

Article in Proceedings of the National Academy of Sciences of the United States of America, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. A Translocation within thebioRxiv : the preprint server for biology · 2026
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Satya Dev PolisettyMolecular Mycology Laboratory, Molecular Biology and Genetics Unit, Jawaharlal Nehru Centre for Advanced Scientific Research, Bengaluru 560064, India.ORCID 0000-0001-9311-7651
Shuvadip DuttaDepartment of Physics, Indian Institute of Technology Bombay, Mumbai 400076, India.ORCID 0000-0002-4373-1589
Rakesh Netha VadnalaNational Centre for Biological Sciences, Tata Institute of Fundamental Research, Bengaluru 560065, India.
Dimple NotaniNational Centre for Biological Sciences, Tata Institute of Fundamental Research, Bengaluru 560065, India.ORCID 0000-0002-9460-8070
Ranjith PadinhateeriDepartment of Biosciences and Bioengineering, Indian Institute of Technology Bombay, Mumbai 400076, India.ORCID 0000-0001-5485-1474
Kaustuv SanyalMolecular Mycology Laboratory, Molecular Biology and Genetics Unit, Jawaharlal Nehru Centre for Advanced Scientific Research, Bengaluru 560064, India.ORCID 0000-0002-6611-4073

Funding

DST | Anusandhan National Research Foundation ANRF/JBG/2025/000335/LSDST | Anusandhan National Research Foundation CRG/2023/001077DST | Anusandhan National Research Foundation JCB/2020/000021
6 · The paper itself

Abstract

Fungal centromeres are clustered near microtubule organizing centers to help adopt the Rabl chromosomal organization. The role of centromere clustering in driving large-scale changes in structural and functional chromatin assembly remains unclear. Here, using Hi-C and superresolution microscopy, we show that cell cycle-dependent centromere declustering and clustering states in

Indexed as

CentromereCryptococcus neoformansGenome, FungalCell CycleChromosomes, FungalTelomere3D genomecentromere clusteringDNA replication timingRabl configuration

Identifiers

PMID41364759
PMCPMC12718375

What OpenQuestion holds

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LicenceCC BY-NC-ND
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.