ArticleIndian pediatrics2026
Role of Family Dynamics in Shaping Coping Strategies Among Children with Transfusion-Dependent Thalassemia.
Article in Indian pediatrics, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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5 authors.
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Abstract
objectiveChildren with transfusion-dependent thalassemia (TDT) face significant physical, emotional, and social challenges that affect their and their families' lives. This study aimed to examine and compare the coping mechanisms of children with TDT and the disease-related impact on their parents' functioning.
methodsThis study enrolled children with TDT aged 8-16 years and age-matched healthy controls (ratio 1:2), and their respective parents. Psychological assessment of the children and their families was conducted using the PedsQL™ Family Impact Module and KidCOPE. Scores obtained from cases and controls were compared using the Mann-Whitney U test.
resultsChildren with TDT (n = 75) showed significantly lower frequency of self-criticism (P = 0.001), higher perceived efficacy of problem-solving as a coping strategy (P = 0.008) and greater use of social support (P = 0.018) compared to the control group (n = 150). The respective parents of children with TDT experienced poorer overall family functioning and lower quality of life compared to parents of healthy children (P = 0.001).
conclusionsThe findings indicate that while children with TDT use certain adaptive coping strategies more frequently than their healthy peers, the overall family functioning and parental quality of life remain significantly compromised. These results highlight the need for psychosocial support addressing both child coping and caregiver well-being.
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