ArticleJournal of robotic surgery2025
The prognostic value of preoperative Neutrophil-to-Albumin ratio (NPAR) for postoperative complications and survival in colorectal cancer patients undergoing robot-assisted surgery: a retrospective cohort study.
Article in Journal of robotic surgery, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
4 citing papers in PubMed.
- Association between preoperative neutrophil percentage-to-albumin ratio and survival outcomes in patients with colorectal cancer undergoing radical surgery: a retrospective study with external validation.Frontiers in oncology · 2026Article
- Neutrophil-Percentage-to-Albumin Ratio Outperforms High-Sensitivity C-Reactive Protein in Predicting Mortality in Acute Heart Failure: Evidence from a Nationwide Prospective Cohort.Journal of inflammation research · 2026Article
- Development and Validation of a Neutrophil Percentage-to-Albumin Ratio-Based Nomogram for Predicting Overall Survival in Locally Advanced Nasopharyngeal Carcinoma.Journal of inflammation research · 2026Article
- Global bibliometric analysis of molecular imaging-guided robotic-assisted surgery: publication dynamics, thematic evolution, authorship patterns, and disciplinary landscape development (1982-2025).Journal of robotic surgery · 2025Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
This study aimed to evaluate the prognostic value of the preoperative neutrophil percentage-to-albumin ratio (NPAR) in predicting postoperative complications and long-term survival in patients undergoing Da Vinci robot-assisted laparoscopic radical resection for colorectal cancer. A retrospective cohort study was conducted, including 230 patients with stage I-III colorectal cancer who underwent robotic-assisted radical surgery at Second Xiangya Hospital of Central South University.from January 2016 to October 2020. Preoperative laboratory parameters within 7 days before surgery were collected to calculate NPAR. Restricted cubic spline (RCS) regression was used to assess the nonlinear association between NPAR and complication risk, with the optimal cutoff value (14.649) determined via the Youden index and validated through 5-fold cross-validation. Postoperative complications were defined as Clavien-Dindo grade ≥ II events within 30 days post-surgery. Firth's penalized logistic regression and ridge regression models, coupled with internal validation, evaluated predictive performance, while Cox proportional hazards and Kaplan-Meier analyses assessed long-term survival. RCS analysis revealed a significant nonlinear positive relationship between NPAR and postoperative complication risk (P < 0.001, P for nonlinearity = 0.002). Patients with NPAR ≥ 14.649 exhibited significantly higher odds of complications (adjusted OR = 4.00, 95% CI: 2.10-7.61, P < 0.001). The ridge-penalized model demonstrated excellent discrimination (AUC = 0.913; optimism-corrected AUC = 0.903) and calibration (Brier score = 0.086; slope = 1.020). Subgroup and sensitivity analyses confirmed robustness across age, sex, tumor location, and comorbidity strata. Elevated NPAR independently predicted poor overall survival (HR = 1.60, 95% CI: 1.21-2.12, P < 0.001), with Kaplan-Meier analysis showing reduced survival in the high-NPAR group (P < 0.001). Preoperative NPAR is a robust and accessible biomarker for predicting short-term complications and long-term outcomes in robotic colorectal cancer surgery. Its integration into preoperative risk assessment can facilitate individualized management and optimize postoperative care.
Indexed as
Identifiers
41364248What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.