ArticleClinical research in cardiology : official journal of the German Cardiac Society2025
Echocardiographic and invasive RV-PA coupling predict mortality after edge-to-edge repair for degenerative mitral regurgitation, while pulmonary artery pulsatility index does not: a single-center observational study.
Article in Clinical research in cardiology : official journal of the German Cardiac Society, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
What it found
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Who cites it
2 citing papers in PubMed.
- Clinical research on pulmonary hypertension from a 2025 perspective: a narrative review.Journal of thoracic disease · 2026Review
- Echocardiographic Assessment of Right Ventricular-Pulmonary Arterial Coupling in Heart Failure: Prognostic Insights from a Systematic Review.Journal of clinical medicine · 2026Review
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Authors and funding
15 authors.
Funding
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Abstract
backgroundRight ventricular-pulmonary artery coupling and the pulmonary artery pulsatility index (PAPi) have emerged as potential prognostic markers in cardiovascular disease. Their utility in patients with degenerative mitral regurgitation (DMR) undergoing transcatheter mitral edge-to-edge repair (M-TEER) remains unclear.
objectivesTo evaluate the prognostic value of RV-PA coupling and PAPi in DMR patients treated with M-TEER.
methodsThis retrospective single-center study included 293 patients with DMR undergoing M-TEER between 2012 and 2022. RV-PA coupling was assessed by echocardiographic tricuspid annular plane systolic excursion (TAPSE) to systolic pulmonary artery pressure (sPAP
resultsRV-PA uncoupling (TAPSE/sPAP
conclusionRV-PA coupling, but not PAPi, predicts mortality and heart failure rehospitalization following M-TEER in DMR patients. These findings highlight the value of RV-PA coupling indices for risk stratification and support their routine use in preprocedural assessment.
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