Evidence map›Paper›PMID 41364211›Full record

SynthesisAesthetic plastic surgery2026

Efficacy and Safety of Er:Glass versus CO

Dingnan Xue, Yating Yu, Xiaoliang Li, Guohua Ma, Jiayi Xie, Yanfeng Xue, Yongfu Cheng, Xiaodong Ren

Abstract readSystematic ReviewMeta-AnalysisComparative Study
PubMed Publisher
In one paragraph

Synthesis in Aesthetic plastic surgery, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pooled it
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

8 authors.

Dingnan XueBeijing University of Chinese Medicine DongFang College, Beijing, 061199, China.
Yating YuShanxi University of Traditional Chinese Medicine, Taiyuan, 030606, China.
Xiaoliang LiFenyang College of Shanxi Medical University, Fenyang, 032200, China.
Guohua MaFenyang College of Shanxi Medical University, Fenyang, 032200, China.
Jiayi XieBeijing University of Chinese Medicine DongFang College, Beijing, 061199, China.
Yanfeng XueChangzhi Yuemei Medical Aesthetic Clinic, Changzhi, 046000, China.
Yongfu ChengFenyang College of Shanxi Medical University, Fenyang, 032200, China.
Xiaodong RenShanxi Health and Medical Vocational College, Jinzhong, 030619, China. xiaodongren1994@163.com.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundFractional laser therapy is a cornerstone for atrophic acne scar treatment. While both ablative fractional CO

methodsA systematic literature search was performed in PubMed, Web of Science, and Cochrane Library up to March 5, 2025. Prospective randomized trials directly comparing Er:Glass and CO

resultsFour studies (98 participants) were included. Pooled analysis showed no significant difference in effective rate (OR = 0.43, 95% CI 0.03-5.98) or patient satisfaction rate (OR = 0.70, 95% CI 0.08-6.25) between lasers. PIH rates were similar (OR = 0.50, 95% CI 0.17-1.45). Er:Glass was associated with significantly less pain (MD = -1.70, 95% CI -2.13 to -1.28), shorter duration of crusting (MD = -3.53, 95% CI -4.55 to -2.52), and duration of erythema (MD = -3.16, 95% CI -3.58 to -2.74).

conclusionEr:Glass and CO LEVEL OF EVIDENCE III: This journal requires that authors assign a level of evidence to each article. For a full description of these Evidence-Based Medicine ratings, please refer to the Table of Contents or the online Instructions to Authors www.springer.com/00266 ."

Indexed as

Acne VulgarisCicatrixLasers, GasLasers, Solid-StateLaser TherapyAtrophyHumansPatient SatisfactionRandomized Controlled Trials as TopicTreatment OutcomeAcne scarsCO2 laserEr:Glass laserFractional laserMeta-analysisPain

Identifiers

PMID41364211

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.