ArticleJournal of medical ultrasonics (2001)2026
Relationship between medial meniscus extrusion and osteophyte formation in early-stage knee osteoarthritis: an ultrasound-based multicenter cross-sectional study.
Article in Journal of medical ultrasonics (2001), 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
3 citing papers in PubMed.
- Meniscal extrusion: Multiple theories, one clinical challenge.Journal of experimental orthopaedics · 2026Article
- Medial meniscus extrusion during gait identifies altered knee mechanical loading in early osteoarthritis of the knee.Journal of experimental orthopaedics · 2026Article
- Explainable machine learning identifies knee morphology thresholds for arthroscopic medial meniscus posterior root tear: a retrospective cohort study.Frontiers in medicine · 2026Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
9 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
purposeMedial meniscus extrusion compromises the ability of meniscus to distribute a load across the knee joint and is recognized as a risk factor for knee osteoarthritis. Despite a positive correlation between medial meniscus extrusion and medial tibial osteophyte width, the sequence of these pathological changes remains unclear. In this multicenter cross-sectional study, we aimed to clarify the relationship between osteophyte formation and medial meniscus extrusion by comparing extrusion distances in knees with and without medial tibial osteophytes.
methodsWe enrolled 207 Japanese patients with early-stage knee osteoarthritis, defined as Kellgren-Lawrence grade ≤ 2. Participants underwent radiography, magnetic resonance imaging, and ultrasonography (US). Knees were categorized into three groups based on the presence of osteophytes: N (no osteophytes), U (osteophytes detected only with US), and O (osteophytes detected with both radiography and US). The medial meniscus extrusion distance was assessed using US.
resultsAmong the 211 knees evaluated, 89 were classified into the N group, 93 into the U group, and 29 into the O group. The medial meniscus extrusion distance was significantly greater in the O group (3.3 ± 1.3 mm) than in both the N (2.3 ± 1.1 mm, p < 0.001) and U (2.6 ± 0.9 mm, p = 0.004) groups. No significant difference was detected between the N and U groups (p = 0.27).
conclusionMedial meniscus extrusion was significantly associated with osteophyte formation in early-stage knee osteoarthritis.
Indexed as
Identifiers
41364182What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.