Evidence map›Paper›PMID 41363795›Full record

ReviewRespiration; international review of thoracic diseases2026

Incidental Pulmonary Nodules: What Should We Do in 2026?

Gerald Schmid-Bindert, Jens Vogel-Claussen, Benjamin-Alexander Bollmann, Joana Lamché, Martin E Eichhorn, Felix Herth

Abstract readReview
In one paragraph

Review in Respiration; international review of thoracic diseases, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Gerald Schmid-BindertUniversity Medical Center Mannheim, Heidelberg University, Mannheim, Germany, gerald.schmid-bindert@umm.de.
Jens Vogel-ClaussenDepartment of Diagnostic and Interventional Radiology, Hannover Medical School, Hannover, Germany.
Benjamin-Alexander BollmannDepartment of Diagnostic and Interventional Radiology, Hannover Medical School, Hannover, Germany.
Joana LamchéAstraZeneca GmbH, Hamburg, Germany.
Martin E EichhornDepartment of Thoracic Surgery, Thoraxklinik, University Hospital Heidelberg, Heidelberg, Germany.
Felix HerthTranslational Lung Research Center (TLRC) Heidelberg, Member of the German Center for Lung Research (DZL), Heidelberg, Germany.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

<p>Background: Incidental pulmonary nodules (IPNs) detected during routine thoracic CT scans offer a promising opportunity to shift lung cancer (LC) diagnoses toward earlier, more curable stages across a broad patient population. Despite their high potential to reduce LC-related mortality, the complexity and heterogeneity of existing guidelines, combined with inefficient follow-up processes, continue to limit the diagnostic and therapeutic benefits of IPN detection. Summary: This article examines the systemic barriers to effective IPN management and outlines strategic solutions, including automation and structured workflows as well as standardized patient communication. With the recent implementation of national lung cancer screening (LCS) programs, new opportunities arise to synergize infrastructures and optimize pulmonary nodule management within a unified framework. Key Message: Therefore, a clearer understanding of how IPNs should be managed - and how they can be integrated into broader early detection strategies - is essential for a truly holistic approach to early LC detection. </p>.

Indexed as

Early Detection of CancerIncidental FindingsLung NeoplasmsMultiple Pulmonary NodulesSolitary Pulmonary NoduleHumansTomography, X-Ray ComputedEarly-stage lung cancerLow-dose computed tomographyLung cancer screeningLung nodule managementStage shift

Identifiers

PMID41363795
PMCPMC12818888

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.