ArticleThe plant genome2025
Genotyping analysis of over 130,000 CIMMYT bread wheat breeding lines: A decade-long effort in optimizing wheat genotyping.
Article in The plant genome, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
4 citing papers in PubMed.
- Genomics for next-generation wheat breeding.The plant genome · 2026Article
- Next-Generation Genotyping: Innovations Driving Plant Genomic Improvement.Life (Basel, Switzerland) · 2026Review
- Skim-sequencing for genomic selection in wheat: a comparison of marker platforms.The plant genome · 2026Article
- Genotyping analysis of over 130,000 CIMMYT bread wheat breeding lines: A decade-long effort in optimizing wheat genotyping.The plant genome · 2025Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
12 authors.
Funding
Abstract
The International Maize and Wheat Improvement Center (CIMMYT) spring bread wheat (Triticum aestivum L.) program represents the largest and most diverse set of elite wheat germplasm globally. From 2013 to 2023, genotyping was conducted on 130,247 bread wheat lines advanced through CIMMYT's bread wheat breeding program with the objective to perform genomic prediction and identify genomic regions associated with important traits such as yield and disease resistance. We constructed and sequenced 636 genotyping-by-sequencing (GBS) libraries, multiplexed at 96- to 384-plex, and generated 30.7 terabases of sequence. Using an optimized TASSEL pipeline, we identified 24,125 high-quality single nucleotide polymorphism on 21 chromosomes. Population genetic clustering of 444 selected lines within 10 pedigrees supported the accuracy of the GBS approach. Genome-wide analysis of nucleotide diversity (π) and minor allele frequency across the entire dataset revealed significantly reduced genetic variation in pericentromeric regions of all chromosomes, which was confirmed by comparison to a genetic outgroup of diverse winter wheat lines. This pattern of low genetic diversity indicates fixation of large centromeric haplotype blocks. The limited diversity in non-recombining regions has critical implications for future genetic gains in wheat breeding. Temporal pairwise F
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.