Evidence map›Paper›PMID 41363124›Full record

ArticleThe Journal of laryngology and otology2026

Tramadol for treatment of neurogenic cough: a retrospective case series.

Benjamin Joseph Rubinstein, Sheela Saidha, John Todd Sinacori

Abstract read
In one paragraph

Article in The Journal of laryngology and otology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Benjamin Joseph RubinsteinMacon & Joan Brock Virginia Health Sciences Eastern Virginia Medical School, Old Dominion University, Norfolk, VA, USA.ORCID https://orcid.org/0000-0003-0060-1087
Sheela SaidhaMacon & Joan Brock Virginia Health Sciences Eastern Virginia Medical School, Old Dominion University, Norfolk, VA, USA.
John Todd SinacoriMacon & Joan Brock Virginia Health Sciences Eastern Virginia Medical School, Old Dominion University, Norfolk, VA, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivesThis study aimed to explore the efficacy of tramadol for neurogenic cough and describe the longitudinal treatment experience.

methodsA retrospective case series of adults with chronic cough who were treated with tramadol for neurogenic cough. A complete response was defined as no pathologic coughing, and a partial response was defined as 50 per cent or greater reduction in severity or frequency.

resultsSixty-nine patients were included: 38 per cent of patients reported a complete response with an additional 33 per cent reporting a partial response. The most common successful dosing regimen was 50 mg twice a day. Age, gender and body mass index did not impact treatment response. Patients with a history of laryngeal surgery were less likely to respond (

conclusionTramadol may be effective and is well tolerated in patients with neurogenic cough.

Indexed as

Analgesics, OpioidCoughTramadolAdultAgedAged, 80 and overChronic DiseaseFemaleHumansMaleMiddle AgedRetrospective StudiesTreatment OutcomeAnalgesics, OpioidTramadolchronic coughcough hypersensitivity syndromeneuromodulatorstramadol

Identifiers

PMID41363124
PMCPMC13058412

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.