Evidence map›Paper›PMID 41363069›Full record

Trial reportThe British journal of nutrition2026

The effect of a person-centred lifestyle programme on cancer-related fatigue in colorectal cancer survivors: a randomised trial.

Judith de Vries-Ten Have, Laura H H Winkens, Auke J C F Verkaar, Sharon A G Bloemhof, Lara Schepers, Koen Manusama, Sandra Beijer, Dirkje W Sommeijer, Ramon R J P van Eekeren, Flip Kruyt and 3 more

Abstract readRandomized Controlled Trial
In one paragraph

Trial report in The British journal of nutrition, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Judith de Vries-Ten HaveChair Group Nutrition and Disease, Division of Human Nutrition and Health, https://ror.org/04qw24q55Wageningen University and Research, Wageningen, The Netherlands.
Laura H H WinkensConsumption and Healthy Lifestyles Chair Group, Wageningen University and Research, Wageningen, The Netherlands.
Auke J C F VerkaarChair Group Nutrition and Disease, Division of Human Nutrition and Health, https://ror.org/04qw24q55Wageningen University and Research, Wageningen, The Netherlands.
Sharon A G BloemhofChair Group Nutrition and Disease, Division of Human Nutrition and Health, https://ror.org/04qw24q55Wageningen University and Research, Wageningen, The Netherlands.
Lara SchepersChair Group Nutrition and Disease, Division of Human Nutrition and Health, https://ror.org/04qw24q55Wageningen University and Research, Wageningen, The Netherlands.
Koen ManusamaChair Group Nutrition and Disease, Division of Human Nutrition and Health, https://ror.org/04qw24q55Wageningen University and Research, Wageningen, The Netherlands.
Sandra BeijerDepartment of Research & Development, Netherlands Comprehensive Cancer Organisation (IKNL), Utrecht, The Netherlands.
Dirkje W SommeijerDepartment of Internal Medicine, Flevohospital, Almere, The Netherlands.
Ramon R J P van EekerenDepartment of Surgery, Rijnstate Hospital, Arnhem, The Netherlands.
Flip KruytDepartment of Surgery, Hospital Gelderse Vallei, Ede, The Netherlands.
Alinda GuitinkDepartment of Gastroenterology, Deventer Hospital, Deventer, The Netherlands.
Ellen KampmanChair Group Nutrition and Disease, Division of Human Nutrition and Health, https://ror.org/04qw24q55Wageningen University and Research, Wageningen, The Netherlands.
Renate M WinkelsChair Group Nutrition and Disease, Division of Human Nutrition and Health, https://ror.org/04qw24q55Wageningen University and Research, Wageningen, The Netherlands.ORCID https://orcid.org/0000-0002-0376-8811

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Cancer-related fatigue is a common problem among colorectal cancer (CRC) survivors even after completion of treatment. In a randomised trial, we assessed the effect of a person-centred lifestyle programme on cancer-related fatigue among CRC survivors who completed treatment. Survivors who completed treatment at least 6 months but no longer than 5 years ago and who were experiencing cancer-related fatigue were randomised to intervention or control group. The intervention group worked with a lifestyle coach for 6 months during twelve sessions to stepwise increase adherence to the World Cancer Research Fund/American Institute of Cancer Research cancer prevention guidelines on healthy diet and physical activity. The control group did not receive lifestyle coaching. Changes in cancer-related fatigue from baseline to 6 months were assessed with the FACIT (Functional Assessment of Chronic Illness Therapy) - Fatigue Scale. As a secondary outcome, we assessed changes in health-related quality of life (HRQoL). Higher scores indicate less fatigue and better HRQoL. Eighty participants were randomised to the intervention group; eighty-one to the control group. Baseline characteristics were similar: mean age 64·1 (sd 10·9) years; 55·3 % were women; and 72 % had colon cancer. There were favourable changes in dietary behaviours and physical activity in the intervention group; the control group did not show changes to the same extent. The programme did not result in statistically significant differential changes over time between intervention and control group in cancer-related fatigue (0·8; 95 % CI -1·6, 3·2) or HRQoL (1·3; 95 % CI -2·2, 4·8). A person-centred lifestyle programme improved the lifestyle of CRC survivors, but the programme was not effective in reducing cancer-related fatigue or in improving HRQoL.

Indexed as

Colorectal NeoplasmsFatigueLife StyleAgedCancer SurvivorsDietDiet, HealthyExerciseFemaleHumansMaleMiddle AgedQuality of LifeSurvivorsBehaviour changeCancer-related fatigueDietInterventionLifestylePersonalisationPhysical activity

Identifiers

PMID41363069
PMCPMC12912834

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.