ArticleHorticulture research2025
The grape berry methylome reveals tissue-specific features associated with metabolism in ripening.
Article in Horticulture research, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
3 citing papers in PubMed.
- Epigenetic orchestration of sugar signaling in plant development and stress adaptation.Horticulture research · 2026Article
- Integrated Analysis of DNA Methylation and Transcriptomic Dynamics in the Grape Variety 'Cabernet Franc' at Early and Late Stages of Fruit Development.Plants (Basel, Switzerland) · 2026Article
- Regulation of gene expression by 5mC DNA methylation during the bolting process of cabbage (Frontiers in plant science · 2026Article
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Authors and funding
11 authors.
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Abstract
DNA methylation is a critical epigenetic regulator in plant development, yet its role in grape berry ripening remains poorly understood. Here, we profiled the genome-wide DNA methylation landscapes of two cultivars, 'Wink' and 'Cabernet Sauvignon', across developmental stages and tissues (skin and pulp tissues), revealing widespread DNA hypermethylation during ripening. We observed a progressive increase in global DNA methylation, particularly in the CHH context, across transposable elements, gene bodies, and adjacent regions during ripening. This hypermethylation was conserved across both varieties and was pronounced in both skin and pulp tissues. Differentially methylated regions (DMRs) revealed tissue-specific methylation patterns, with skin and pulp exhibiting distinct hypermethylation dynamics. Further analysis demonstrated that these tissue-specific hypermethylation dynamics are partially attributable to pre-existing methylation differences between skin and pulp at earlier developmental stages. Functional analysis demonstrated that DNA methylation inhibitors (zebularine and RG108) delayed berry ripening
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Registered trials
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